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神经生长，修复再生？突触素（Synaptophysin）抗体的秘密 - 每日生物评论

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首页科研产品发现样品检测分析常见蛋白与IgG正文

神经生长，修复再生？突触素（Synaptophysin）抗体的秘密

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突触素(synaptophysin, SYP )是一种与突触功能密切相关的膜蛋白，Jahn于1885年首先从大鼠脑突触囊泡中提取，因其相对分子质量为38KDa，又称为p38。它广泛存在于机体所有神经终末,特异性地分布于突触前囊泡膜上.因其与神经生长,修复再生和突触重塑密切相关,成为近年来基础医学和康复医学研究的热点。

 

 

据报道，突触素（synaptophysin）出现在大脑、脊髓、视网膜的突触前小泡，也出现在类似的肾上腺髓质小泡以及神经肌肉连接点。突触素（synaptophysin）可能参与突触囊泡的形成和胞吐。

 

突触素（synaptophysin）在神经内分泌肿瘤中广泛表达，包括神经母细胞瘤、神经节神经母细胞瘤、嗜铬细胞瘤和非嗜铬细胞副神经节瘤。突触素在上皮型神经内分泌肿瘤中也有表达，包括垂体腺瘤、胰岛细胞瘤、甲状腺髓样癌、甲状旁腺瘤、支气管肺和胃肠道类癌、支气管肺和胃肠道神经内分泌癌以及皮肤神经内分泌癌。

 

研究靠得住，抗体第一步！作为专业的生命科学解决方案供应商，艾美捷为您推荐这个纵横Nature, Cell的超能打的101组合成员：突触素（synaptophysin）101 011，来自德国（SySy）

 

 

产品货号

101 011

产品名称

Synaptophysin 1（抗体）

品牌

Synaptic Systems中国区总代理，艾美捷科技

应用类型

WB: 1 : 10000 (AP staining)

IP: yes

ICC: 1 : 100 up to 1 : 1000

IHC: 1 : 500 up to 1 : 1000

IHC-P/FFPE: 1 : 500 up to 1 : 1000

EM: yes

ELISA: yes (see remarks)

反应种属

人，小鼠，大鼠，哺乳动物

（与斑马鱼和其它脊椎动物有微弱反应）

抗原决定簇

大鼠突触素1（Synaptophysin 1）的第219-307位氨基酸(UniProt Id: P07825)

产品说明

50ug特异性抗体，冻干粉形式. 使用免疫原进行亲和纯化. 添加了白蛋白和叠氮化物以起到稳定作用.

溶解建议

加入50ul无菌去离子水，获得1mg/ml的PBS溶液.然后分装保存与-20℃，直到使用。

说明书下载

点击下载

 

发表文章超160+：Nature, Cell，Science 课代表~

WB（78+）

Vesicular Glutamate Transporters (SLCA17 A6, 7, 8) Control Synaptic Phosphate Levels.

Cheret C, Ganzella M, Preobraschenski J, Jahn R, Ahnert-Hilger G

Cell reports (2021) 342: 108623. 101 011 WB; tested species: mouse

Cooperative function of synaptophysin and synapsin in the generation of synaptic vesicle-like clusters in non-neuronal cells.

Park D, Wu Y, Lee SE, Kim G, Jeong S, Milovanovic D, Camilli P, Chang S

Nature communications (2021) 121: 263. 101 011 WB, ICC; tested species: cos cells

Neuromodulator Signaling Bidirectionally Controls Vesicle Numbers in Human Synapses.

Patzke C, Brockmann MM, Dai J, Gan KJ, Grauel MK, Fenske P, Liu Y, Acuna C, Rosenmund C, Südhof TC

Cell (2019) 1792: 498-513.e22. 101 011 WB, ICC; tested species: mouse

IP（6+）

Identification and characterization of the BRI2 interactome in the brain.

Martins F, Marafona AM, Pereira CD, Müller T, Loosse C, Kolbe K, da Cruz E Silva OAB, Rebelo S

Scientific reports (2018) 81: 3548. 101 011 WB, IP; tested species: rat

ICC（42+）

Bassoon Controls Presynaptic Autophagy through Atg5.

Okerlund ND, Schneider K, Leal-Ortiz S, Montenegro-Venegas C, Kim SA, Garner LC, Waites CL, Gundelfinger ED, Reimer RJ, Garner CC

Neuron (2018) 973: 727. 101 011 ICC; tested species: mouse

Synaptic nanomodules underlie the organization and plasticity of spine synapses.

Hruska M, Henderson N, Le Marchand SJ, Jafri H, Dalva MB

Nature neuroscience (2018) 215: 671-682. 101 011 ICC; tested species: rat

CAPS-1 and CAPS-2 are essential synaptic vesicle priming proteins.

Jockusch WJ, Speidel D, Sigler A, Sørensen JB, Varoqueaux F, Rhee JS, Brose N

Cell (2007) 1314: 796-808. 101 011 ICC

IHC（34+）

Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1.

Rathjen T, Yan X, Kononenko NL, Ku MC, Song K, Ferrarese L, Tarallo V, Puchkov D, Kochlamazashvili G, Brachs S, Varela L, et al.

Nature neuroscience (2017) 208: 1096-1103. 101 011 IHC; tested species: mouse

Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins.

Wilhelm BG, Mandad S, Truckenbrodt S, Kröhnert K, Schäfer C, Rammner B, Koo SJ, Claßen GA, Krauss M, Haucke V, Urlaub H, et al.

Science (New York, N.Y.) (2014) 3446187: 1023-8. 101 011 WB, ICC, IHC; tested species: mouse,rat

EM（1+）

Synaptic membrane proteins form stable microdomains in early endosomes.

Geumann U, Schäfer C, Riedel D, Jahn R, Rizzoli SO

Microscopy research and technique (2010) 736: 606-17. 101 011 ICC, EM

ELISA（1+）

Synapsin-dependent reserve pool of synaptic vesicles supports replenishment of the readily releasable pool under intense synaptic transmission.

Vasileva M, Horstmann H, Geumann C, Gitler D, Kuner T

The European journal of neuroscience (2012) 368: 3005-20. 101 011 ELISA

 

部分结果图展示：

WB

ICC

IHC

IHC-P

 

运输条件

所有抗体和对照蛋白/肽以冻干粉状态（真空冷冻干燥）运输，室温下可以在数周内保持稳定和活性。

 

收到产品之后的操作和样品瓶的储存

无标记和生物素标记抗体以及对照蛋白在重悬前应保存在 4°C 的条件下。 在冻干状态下不要存放在冷冻柜里！低于零摄氏度会导致反应性降低。

 

重悬

所有抗体均由PBS冻干。用PBS溶解抗体冻干粉，请参照数据手册定量添加去离子水。大容量溶解时，先添加去离子水，然后适量的PBS和蛋白稳定剂（例如BSA）至2%的最终浓度。添加蛋白稳定剂时请注意，部分抗体已经含有血清白蛋白。制作重悬溶液时请小心打开盖子。添加去离子水后，轻微晃动溶液。为使液体聚集在样品瓶底部，可以使用离心机离心。操作离心机时，可以在50ml离心管中样品瓶下面铺垫废纸，以方便离心后取出。

为抑制细菌生长，可以添加少量的叠氮化物或硫柳汞作为防腐剂。该操作特别适用于分量包装在4°C条件下保存。可以向不带标记的一抗添加甘油，以避免冻融循环。

................................................................................................

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发布日期：2021年05月07日  所属分类：常见蛋白与IgG

标签：SynaptophysinSYP突触体素突触素突触素抗体

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突触素（Synaptophysin）抗体

2021-04-27 10:21   点击次数： 关键词： 突触素 突触体素 突触素抗体 Synaptophysin,SYP

突触素(synaptophysin, SYP )是一种与突触功能密切相关的膜蛋白，Jahn于1885年首先从大鼠脑突触囊泡中提取，因其相对分子质量为38KDa，又称为p38。它广泛存在于机体所有神经终末,特异性地分布于突触前囊泡膜上.因其与神经生长,修复再生和突触重塑密切相关,成为近年来基础医学和康复医学研究的热点。  据报道，突触素（synaptophysin）出现在大脑、脊髓、视网膜的突触前小泡，也出现在类似的肾上腺髓质小泡以及神经肌肉连接点。突触素（synaptophysin）可能参与突触囊泡的形成和胞吐。 突触素（synaptophysin）在神经内分泌肿瘤中广泛表达，包括神经母细胞瘤、神经节神经母细胞瘤、嗜铬细胞瘤和非嗜铬细胞副神经节瘤。突触素在上皮型神经内分泌肿瘤中也有表达，包括垂体腺瘤、胰岛细胞瘤、甲状腺髓样癌、甲状旁腺瘤、支气管肺和胃肠道类癌、支气管肺和胃肠道神经内分泌癌以及皮肤神经内分泌癌。 研究靠得住，抗体第一步！作为专业的生命科学解决方案供应商，艾美捷为您推荐这个纵横Nature, Cell的超能打的101组合成员：突触素（synaptophysin）101 011，来自德国（SySy）  

产品货号

101 011

产品名称

Synaptophysin 1（抗体）

品牌

Synaptic Systems中国区总代理，艾美捷科技

应用类型

WB: 1 : 10000 (AP staining) IP: yes ICC: 1 : 100 up to 1 : 1000 IHC: 1 : 500 up to 1 : 1000 IHC-P/FFPE: 1 : 500 up to 1 : 1000 EM: yes ELISA: yes (see remarks)

反应种属

人，小鼠，大鼠，哺乳动物 （与斑马鱼和其它脊椎动物有微弱反应）

抗原决定簇

大鼠突触素1（Synaptophysin 1）的第219-307位氨基酸(UniProt Id: P07825)

产品说明

50ug特异性抗体，冻干粉形式. 使用免疫原进行亲和纯化. 添加了白蛋白和叠氮化物以起到稳定作用.

溶解建议

加入50ul无菌去离子水，获得1mg/ml的PBS溶液.然后分装保存与-20℃，直到使用。

说明书下载

点击下载

 发表文章超160+：Nature, Cell，Science 课代表~

WB（78+）

Vesicular Glutamate Transporters (SLCA17 A6, 7, 8) Control Synaptic Phosphate Levels. Cheret C, Ganzella M, Preobraschenski J, Jahn R, Ahnert-Hilger G Cell reports (2021) 342: 108623. 101 011 WB; tested species: mouse Cooperative function of synaptophysin and synapsin in the generation of synaptic vesicle-like clusters in non-neuronal cells. Park D, Wu Y, Lee SE, Kim G, Jeong S, Milovanovic D, Camilli P, Chang S Nature communications (2021) 121: 263. 101 011 WB, ICC; tested species: cos cells Neuromodulator Signaling Bidirectionally Controls Vesicle Numbers in Human Synapses. Patzke C, Brockmann MM, Dai J, Gan KJ, Grauel MK, Fenske P, Liu Y, Acuna C, Rosenmund C, Südhof TC Cell (2019) 1792: 498-513.e22. 101 011 WB, ICC; tested species: mouse

IP（6+）

Identification and characterization of the BRI2 interactome in the brain. Martins F, Marafona AM, Pereira CD, Müller T, Loosse C, Kolbe K, da Cruz E Silva OAB, Rebelo S Scientific reports (2018) 81: 3548. 101 011 WB, IP; tested species: rat

ICC（42+）

Bassoon Controls Presynaptic Autophagy through Atg5. Okerlund ND, Schneider K, Leal-Ortiz S, Montenegro-Venegas C, Kim SA, Garner LC, Waites CL, Gundelfinger ED, Reimer RJ, Garner CC Neuron (2018) 973: 727. 101 011 ICC; tested species: mouse Synaptic nanomodules underlie the organization and plasticity of spine synapses. Hruska M, Henderson N, Le Marchand SJ, Jafri H, Dalva MB Nature neuroscience (2018) 215: 671-682. 101 011 ICC; tested species: rat CAPS-1 and CAPS-2 are essential synaptic vesicle priming proteins. Jockusch WJ, Speidel D, Sigler A, Sørensen JB, Varoqueaux F, Rhee JS, Brose N Cell (2007) 1314: 796-808. 101 011 ICC

IHC（34+）

Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1. Rathjen T, Yan X, Kononenko NL, Ku MC, Song K, Ferrarese L, Tarallo V, Puchkov D, Kochlamazashvili G, Brachs S, Varela L, et al. Nature neuroscience (2017) 208: 1096-1103. 101 011 IHC; tested species: mouse Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins. Wilhelm BG, Mandad S, Truckenbrodt S, Kröhnert K, Schäfer C, Rammner B, Koo SJ, Claßen GA, Krauss M, Haucke V, Urlaub H, et al. Science (New York, N.Y.) (2014) 3446187: 1023-8. 101 011 WB, ICC, IHC; tested species: mouse,rat

EM（1+）

Synaptic membrane proteins form stable microdomains in early endosomes. Geumann U, Schäfer C, Riedel D, Jahn R, Rizzoli SO Microscopy research and technique (2010) 736: 606-17. 101 011 ICC, EM

ELISA（1+）

Synapsin-dependent reserve pool of synaptic vesicles supports replenishment of the readily releasable pool under intense synaptic transmission. Vasileva M, Horstmann H, Geumann C, Gitler D, Kuner T The European journal of neuroscience (2012) 368: 3005-20. 101 011 ELISA

 部分结果图展示：

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ICC

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IHC-P

 运输条件 所有抗体和对照蛋白/肽以冻干粉状态（真空冷冻干燥）运输，室温下可以在数周内保持稳定和活性。 收到产品之后的操作和样品瓶的储存 无标记和生物素标记抗体以及对照蛋白在重悬前应保存在 4°C 的条件下。 在冻干状态下不要存放在冷冻柜里！低于零摄氏度会导致反应性降低。 重悬所有抗体均由PBS冻干。用PBS溶解抗体冻干粉，请参照数据手册定量添加去离子水。大容量溶解时，先添加去离子水，然后适量的PBS和蛋白稳定剂（例如BSA）至2%的最终浓度。添加蛋白稳定剂时请注意，部分抗体已经含有血清白蛋白。制作重悬溶液时请小心打开盖子。添加去离子水后，轻微晃动溶液。为使液体聚集在样品瓶底部，可以使用离心机离心。操作离心机时，可以在50ml离心管中样品瓶下面铺垫废纸，以方便离心后取出。为抑制细菌生长，可以添加少量的叠氮化物或硫柳汞作为防腐剂。该操作特别适用于分量包装在4°C条件下保存。可以向不带标记的一抗添加甘油，以避免冻融循环。................................................................................................看到这儿，您心动了吗？马上联系小艾吧！或者扫描下方二维码，即可联系您的专属客服哦~  作为一家具有高端的技术实力、先进的经营管理水平和完善的市场销售体系的生物高科技企业，总部位于武汉光谷高新技术开发区，服务面向全国。艾美捷科技是集进口试剂、实验室耗材销售、技术服务与合约开发为一体的专业化高科技公司，为用户提供专业的前沿资讯、完备的产品、整合的解决方案，及优质的物流服务。 艾美捷科技与国内外优秀的生物试剂供应商优保持着密切的合作关系，目前已成为众多国际知名品牌的中国总代理或一级代理，主要包括：AmyJet、AmyJet、AAT Bioquest、Abbexa、Abnova、Agrisera、Anogen、Biosensis、Biovision、Caisson Labs、Cell Biolabs、Cytoskeleton、Demeditec、Duchefa、Epigentek、Equitech-Bio、EXBio、Fitzgerald、GeneCopoeia、Hycult Biotech、ImmunoReagents、Jackson、LifeSensors、LigaTrap、Mabtech、Matreya、Norgen Biotek、Origene、ProImmune、ProSpec、ScyTek、Solis BioDyne、SouthernBiotech、StressMarq、SySy、US Biological、TRC等，可以在短时间内为用户提供专业的前沿资讯、完备的产品及物流服务。  

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Shanghai Yaohua Pilkington Glass Group Co.,Ltd. (Abbr: SYP) was founded in November 1983. It became one of the first public listed glass manufacturers in China with its IPO completed in 1993.

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Shanghai Yaohua Pilkington Glass Co., Ltd was founded, which was one of the earliest joint venture companies at that time.

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Shanghai Yaohua Pilkington Glass Group Co.,Ltd. (Abbr: SYP) was founded in November 1983.It became one of the first public listed glass manufacturers in China with its IPO completed in1993.Currently SYP has three major Businesses , float glass, architectural processed glass and autoglass, with total assets over RMB 7.3 billion. SYP can produce 680,000 tons float glass, 50million square meters architectural processed glass and 4 million sets of autoglass annually.SYP has long been certified with ISO9001: 2000 quality management system and the ISO14001international certificate of SGS in China. Moreover, SYP was awarded Shanghai Famous Trademark at the end of 2005. The float glass and IGU products were awarded the China Top Brandproducts.SYP architectural processed glass products have been awarded Shanghai Top 100 Brand Name products for consecutive eight years.While maintaining a leading position in China’s glass industry, SYP is striving to establish itself as a leading multinational glass manufacturer.

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1983

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Shanghai Yaohua Pilkington Glass Co., Ltd was founded, which was one of the earliest joint venture companies at that time.

1987

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After importing “Float glass process” of Pilkington UK, SYP first float glass line with 180,000 tons’ annual capacity was built. It became a company which can produce all kinds of high quality clear float glass.

1993

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It became one of the first public listed glass manufactures in China after restructuring and listing.

1995

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The second tinted float glass line was built with 90.000 tons’ annual capacity, which ended the condition in China that tinted float glass was fully depended on import.

1997

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Shanghai Yaohua Pilkington Glass Co., Ltd Kangqiao glass processing base went into operation.

2000

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Shanghai Glass and Glass Processing R&D center was established in SYP.SYP bought “Shanghai FuHua Glass Co., Ltd”, which Ford of American invested in China and renamed it to “SYP Kangqiao Autoglass Co., Ltd.”SYP bought “Guangdong float glass Co., ltd”, which PPG of American invested in China and renamed it to “Guangdong SYP Glass Co., Ltd.”

2003

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SYP bought “Tianjin NSG float glass Co., Ltd”, which NSG of Japanese invested in China and renamed it to “Tianjin SYP Glass Co., ltd”

2004

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“Shanghai SYP Engineering Glass Co., ltd” went into production.

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“Jiangsu Pilkington SYP Glass Co., Ltd.” went into production.“Changshu SYP Special Glass Co., Ltd. “went into production.SYP brand float glass, Low E coated glass, tempered glass, Insulated glass were regarded as ”State Inspection exemption product” by General Administration of Quality Supervision, Inspection and Quarantine of the PRC.

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手把手教你基因进化树的构建（一） - 知乎

手把手教你基因进化树的构建（一） - 知乎切换模式写文章登录/注册手把手教你基因进化树的构建（一）生信果对于基因进化树的构建，大家应该都很苦恼吧。最近小果刚好需要构建进化树，在经过学习之后，也掌握了如何建树。那么现在就让小果来带大家一步步从序列数据的下载，再到基因进化树的建立，详细地手把手教学吧！一、蛋白质序列数据的下载在这里我们将在NCBI数据库中，搜寻Syp synaptophysin蛋白质的fastq序列作为数据准备。其中Synaptophysin（SYP）是一种神经元内高度保守的膜蛋白，它主要存在于突触小泡膜上，并参与突触传递和神经递质释放的过程。它被广泛用作神经末梢和神经内分泌肿瘤的免疫组化标记物，可以用于帮助鉴定和分类这些肿瘤。因此，在病理学和临床诊断中，鉴定SYP的表达水平可以提供有用的信息，对于诊断和治疗策略的制定具有重要意义。如图所示，在选择了Protein之后，我们在NCBI的搜索框中搜寻Syp synaptophysin的界面如下：二、搜寻检索的处理因为在搜寻的过程中，搜寻的结果太多，为了能够进一步的筛查数据，我们可以在搜寻栏中增添逻辑运算符，如NOT、OR、AND等。如图所示，我们为了进一步地去除标题中包含hypothetical的数据，将在检索框中，输入Syp synaptophysin NOT hypothetical[title] ，然后需要注意的是，我们在后面需要备注[title] 与此同时，我们也可以在Search details中复制搜索的结果并保存，在日后需要再次搜寻同样的结果的时候，可以直接复制上去紧接着，我们点击Send to按钮，对已经选取不同物种的蛋白质序列进行下载，在这里我们选取十种左右不同的物种的SYP蛋白序列。选择FASTA的格式，点击Create File按钮，将下载到sequence.fasta的文件中三、下载序列的处理为了进一步地使得后面构建的进化树中，能够很好地观察到物种名，我们在这里需要对>后面的id和物种名进行处理，将id名替换成为物种名所以在此我们将使用正则表达式进行替换，如图所示为替换的方式，其中的Find what中的字符为>([^ ]+).*\[(.*)\]>([^ ]+).*\[(.*)\]的意思是：匹配以大于符号（>）开头，之后是一个或多个非空格字符的字符串，然后是一个方括号（[]）括起来的任意字符。而当使用\2时，它表示对第二个捕获组的引用。这意味着，如果正则表达式中的模式匹配了一个字符串，并且第二个捕获组捕获了一些内容，那么\2将被替换为该捕获组中所捕获的内容。例如，如果应用正则表达式>([^ ]+).*\[(.*)\]于字符串>Hello [World]，那么\2将被替换为World，因为World是第二个捕获组所捕获的内容。所得的结果如下：好啦，对于已经下载好的蛋白质序列也处理了，我们接下来就可以进行基因进化树的构建了！在下一篇中，小果将给大家带来更详细的，去使用mega软件进行进化树的构建的过程！是不是非常期待呢？发布于 2023-10-17 11:10・IP 属地上海基因生信分析​赞同 2​​1 条评论​分享​喜欢​收藏​申请

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耀皮玻璃_百度百科

_百度百科 网页新闻贴吧知道网盘图片视频地图文库资讯采购百科百度首页登录注册进入词条全站搜索帮助首页秒懂百科特色百科知识专题加入百科百科团队权威合作下载百科APP个人中心收藏查看我的收藏0有用+10耀皮玻璃播报讨论上传视频上海耀华皮尔金顿玻璃股份有限公司上海耀华皮尔金顿玻璃股份有限公司前身上海耀华皮尔金顿玻璃公司，1983年6月7日由中国建材技术装备总公司，上海耀华玻璃厂，中行上海信托咨询公司，皮尔金顿国际控股公司BV和以色列联合发展公司（香港）共同投资成立。公司名称上海耀华皮尔金顿玻璃股份有限公司外文名Shanghai Yaohua Pilkington Glass Co., Ltd.总部地点上海市浦东新区济阳路100号经营范围非金属矿物制品业证券代码600819证券简称耀皮玻璃注册资本73125.008万元工商登记号企股沪总字第019022号上市时间1994年01月28日目录1公司发展2服务宗旨3企业荣誉4分支机构▪天津▪广东▪江苏▪常熟▪上海耀皮▪上海耀皮▪天津▪耀皮汽车▪耀皮公司5证券资料6投资亮点7十大股东8最大股东易主公司发展播报编辑耀皮玻璃上海耀华皮尔金顿玻璃股份有限公司（中文简称“耀皮玻璃”，英文简称“SYP”）成立于1983年，是当时国内最大的中英合资企业，1993年改制上市，总部位于上海市浦东新区济阳路100号。公司拥有市级企业技术中心及国内一流水平的检测中心，主要业务覆盖浮法玻璃、建筑加工玻璃和汽车玻璃三大领域。截至2006年底，公司总资产超过46亿元，销售收入突破17亿元。在浮法玻璃领域，公司不断发展壮大。2000年和2003年，公司先后收购了广东浮法玻璃有限公司（现更名为广东耀皮玻璃有限公司）和天津日板浮法玻璃有限公司（现更名为天津耀皮玻璃有限公司）。2005年，公司与皮尔金顿合资成立江苏皮尔金顿耀皮玻璃有限公司，与格拉斯林有限公司合资成立常熟耀皮特种玻璃有限公司。如今公司已拥有采用英国Pilkington技术、美国PPG技术和日本板硝子（NSG）技术的优质浮法玻璃生产线。浮法玻璃业务下属上海济阳工厂、广东耀皮玻璃有限公司、天津耀皮玻璃有限公司、江苏皮尔金顿玻璃有限公司共五条生产线。主要产品有：1.8mm-25mm优质透明浮法玻璃、2mm-12mm优质F绿、H绿、蓝、灰、黑本体着色浮法玻璃。另有涉足太阳能电池领域的超白压延玻璃生产线一条，是公司在节能、环保领域的新突破。公司是国内商用建筑玻璃的优秀供应商。1995年，公司参股上海阳光镀膜玻璃有限公司，并受托进行管理。之后，公司先后斥资近7亿元在上海康桥工业园区建成了综合性建筑玻璃加工基地。2002年公司对上海阳光镀膜玻璃有限公司全面控股。2012年，公司在上海和京津两地拥有四家工厂，数十条玻璃深加工生产线，是国内加工玻璃行业规模最大、设备最先进、综合配套能力最强的玻璃深加工企业之一。主要产品有：镀膜、中空、夹层、钢化、彩釉、热弯、家具等各种安全、环保、节能、装饰系列加工玻璃。耀皮玻璃2000年，公司收购了上海福华汽车玻璃有限公司（现更名为上海耀皮汽车玻璃有限公司），开始涉足汽车玻璃领域。2004年底，年产80万套的汽车玻璃新厂在康桥工业园区建成投产。公司引进英国皮尔金顿汽车玻璃成套加工技术和设备，主营各类汽车用前挡印刷曲面夹层玻璃，汽车用单曲面钢化玻璃，热线印刷玻璃及各类汽车玻璃总成。产品的产量、质量和市场占有率均在同行中名列前茅。公司自投产以来，坚持走市场、质量、效益型的发展道路，在市场经济大潮中顽强拚搏、艰苦创业，企业规模不断扩大，管理水平不断提高。1994年3月，耀皮玻璃在中国玻璃行业第一个建立了经国际权威机构认证的ISO9002质量体系；2000年7月，公司又率先通过了ISO14001环境管理体系国际认证。2012年，公司产品分别通过3C、澳标、美国、英国等国际认证，并形成了较强的新产品独立开发能力。公司已申请和获得了10多项发明专利，多次获得各级各类新品开发殊荣。耀皮商标是上海市著名商标，中国名牌产品，国家免检产品。多年的努力使公司的生产效率和经济效益在同行业一直保持较高水平，公司曾三次被评为全国十佳合资企业，自1989年以来被连续评为全国外商投资创汇创利双优企业。比赢利的增长和获得的荣誉更为重要的是，公司在实践中培养了一批高素质的员工队伍，形成了勇于开拓的作风。“永远有新的追求”是公司的理念。自成立以来，公司从未满足于过去的成绩，从未驻足不前、等待观望，而是沿着既定的目标不断向前发展，力求将公司建成积极进取，中国声誉最佳、实力最强的玻璃制造与深加工企业，并为早日跻身国际一流企业而不懈奋斗！服务宗旨播报编辑耀皮玻璃1、“以客为尊”：不管发生什么情况，我们都要努力善待顾客。2、耐心对待每一位顾客，对待顾客的热情不能因某些顾客的不友好态度而打折扣。3、平等对待每一位顾客，不要责备或训斥顾客，也不要让他们感到在你眼中无关紧要。4、以友好的态度给顾客提供帮助和建议，让他（她）感觉到受欢迎和受尊重。5、以满足顾客的需要为己任。6、不自作主张地处理顾客的问题和抱怨。7、在没有把问题弄清楚之前，不要把顾客及其需求推给同事。8、努力获得顾客的反馈意见，不管它是肯定或否定，并分析原因和提出改进措施。企业荣誉播报编辑中国名牌产品公司自1986年起已经6次被评为外商投资先进技术型企业国家免检产品产品质量免检证书公司自2001年起连续被评为高新技术企业公司自1996年起连续10年被评为外商投资双优企业上海市知识产权示范企业上海市著名商标证书自1990年起连续16年被评为上海市文明单位自1999年起已经6次被评为上海名牌产品守合同重信用企业合同信用等级认定证书分支机构播报编辑天津天津耀皮玻璃有限公司（原中日合资企业天津日板浮法玻璃有限公司）成立于1995年4月，占地面积31公顷，位于天津滨海新区大港区北围堤路炼油厂西侧，距离天津市中心40km，塘沽港30km，交通十分便利。厂内有铁路专用线，便于原料、燃料和产品的运输。广东广东耀皮玻璃有限公司（简称广东耀皮或GSYP）原名广东浮法玻璃有限公司，于1984年由招商局轮船股份有限公司、中国北方工业公司深圳分公司、广东国际信托投资公司、深圳市建筑材料工业公司四家股东组成的南方玻璃有限公司与由美国PPG国际工业公司、泰国郑亮荫投资公司组成的香港泛华亚有限公司签约成立，于1987年7月建成投产。公司坐落于深圳经济特区蛇口工业区，占地约13公顷。江苏江苏皮尔金顿耀皮玻璃有限公司(JSYP)由上海耀华皮尔金顿玻璃股份有限公司（中方）与英国皮尔金顿有限公司（外方）合资组建。公司投资总额为9668万美元，其中注册资本为4833万美元。江苏皮尔金顿耀皮玻璃有限公司位于江苏省常熟经济开发区，总占地面积约877亩。北枕长江，紧邻国家一类开放口岸--常熟港，距上海耀皮玻璃总部约130公里，西接在建的苏通大桥，沿江高速穿境而过，水陆交通便利。常熟常熟耀皮特种玻璃有限公司(简称“常熟耀皮”或“CSYP”)位于江苏省常熟经济开发区，一期工程占地面积约80亩。常熟耀皮特种玻璃有限公司北枕长江，紧邻国家一类开放口岸--常熟港，距上海130公里，西接苏通大桥，沿江高速穿境而过，水陆交通便利，水、电、气等配套设施完善。公司由上海耀华皮尔金顿玻璃股份有限公司（SYP）与香港格拉斯林有限公司合资组建，投资总额2500万美元。上海耀皮上海耀皮建筑玻璃有限公司是上海耀华皮尔金顿玻璃股份有限公司的控股子公司，其日常经营由上海耀华皮尔金顿玻璃股份有限公司加工玻璃事业部负责。公司前身上海阳光镀膜玻璃有限公司，成立于1992年7月，主营生产和销售镀膜玻璃、钢化玻璃、中空玻璃及其系列深加工产品。公司的投资方包括上海耀华皮尔金顿玻璃股份有限公司、上海建筑材料（集团）总公司、北京中北窑业技术公司等组成。上海耀皮上海耀皮工程玻璃有限公司是一家中外合资企业，成立于2002年10月，主要生产和销售钢化玻璃、镀膜玻璃、中空玻璃及其系列深加工产品。公司的投资方由上海耀皮建筑玻璃有限公司、香港格拉斯林有限公司组成，公司日常经营由上海耀华皮尔金顿玻璃股份有限公司加工玻璃事业部负责。天津天津耀皮工程玻璃有限公司是一家中外合资企业，成立于2006年12月，主营生产和销售钢化玻璃、镀膜玻璃、中空玻璃及其系列深加工产品，并提供产品的售后技术服务。公司的投资方由上海耀皮建筑玻璃有限公司、格拉斯林有限公司组成，公司的日常经营管理由上海耀华皮尔金顿玻璃股份有限公司加工玻璃事业部负责。耀皮汽车上海耀皮汽车玻璃有限公司（简称“耀皮康桥汽玻”或者“SYPKA”）的前身为上海福华玻璃有限公司，1994年7月成上海耀皮汽车玻璃有限公司立，投资方为美国福特公司和上海建筑材料（集团）总公司。2004年公司成为由上海耀华皮尔金顿玻璃股份有限公司（简称“耀皮玻璃”或者“SYP”）、上海建筑材料（集团）总公司两方的合资企业，并更名为“上海耀皮汽车玻璃有限公司”。耀皮公司上海耀皮康桥汽车玻璃有限公司是一家专业从事OEM汽车玻璃及玻璃总成研发、制造与销售的中外合资企业，公司提供各类汽车前风挡、车门、侧窗、后风挡玻璃，2012年被评为“上海市外商投资先进技术企业”。公司引进了世界上最先进的汽车玻璃设计和制造技术，并进行消化吸收和自主创新。自主开发的半钢化夹层车门玻璃，可吸收紫外线99%，抗冲击力较普通玻璃提高了20倍，降低了6分贝风噪音，率先为国产高档轿车提供了高级隔音夹层汽车安全玻璃。证券资料播报编辑耀皮玻璃证券简称 耀皮玻璃证券类型A股曾用名 G耀皮上市状态 已经上市上市国家/地区 中国大陆上市交易所上海证券交易所上市日期 1994-01-28发行价(元) 6.8上市首日收盘价(元) 14.7上市首日涨跌幅(%) 116.18上市首日换手率(%) 19.22主承销商： 上海万国证券公司上市推荐人： 上海万国证券公司审计机构： 上海上会会计师事务所有限公司经办会计师： 张文枝 巢旭投资亮点播报编辑1. 公司是国内商用建筑玻璃的优秀供应商。年产80万套的汽车玻璃新厂已在康桥工业园区建成投产,成为上海通用、上海大众、东风悦达起亚、南京依维柯、福建东南等国内诸多汽车厂家的合格供应商并批量供货。2. 公司2009年前三季度主要财务指标:每股收益-0.1340(元),每股净资产2.6400(元),净资产收益率-5.0840%,营业收入1696352409.4700(元),同比增减-13.8470%;归属上市公司股东的净利润-98059236.11(元),同比增减-336.9926%。3. 公司可用于投资理财的限额为人民币5亿元，其中用于专户理财的限额不超过人民币2亿元,其余部分可用于购买新股或由金融机构经批准发行的低风险理财产品,上述投资理财的期限至2010年6月止。4. 截止2009年5月6日,东方资产累计减持公司无限售条件流通股7182850股(占公司总股本的0.98%),尚持有公司无限售条件流通股36305498股(占公司总股本的4.96%)。5. 控股子公司广东耀皮玻璃有限公司由于熔窑临近大修且产品结构不够合理,且经营业绩不够理想。公司对广东耀皮日熔化量为550吨的浮法玻璃生产线进行停产,并作冷修技术改造准备。6. 公司2008年度利润分配方案为:A股每10股派0.20元人民币(含税);B股每股派0.002925美元(含税)。股权登记日:2009年7月29日(A股);2009年8月3日(B股);除息日:2009年7月30日。十大股东播报编辑截至日期：2009-06-30 公告日期：2009-08-27编号股东名称持股数量持股比例股本性质1皮尔金顿国际控股公司BV14195.90万19.41%流通A股2中国复合材料集团有限公司11893.46万16.26%流通A股3上海耀华玻璃厂11799.71万16.14%流通A股4上海建筑材料（集团）总公司7450.87万10.19%流通A股5中国东方资产管理公司2836.84万3.88%流通A股6TOYO SECURITIES ASIA LTD. A/C CLIENT909.40万1.24%流通B股7孙文雄514.29万0.70%流通B股8NAITO SECURITIES CO., LTD.494.02万0.68%流通B股9申银万国证券股份有限公司421.33万0.58%流通A股10李丽蓁250.79万0.34%流通B股最大股东易主播报编辑证券代码：600819 证券简称：耀皮玻璃 编号：临2011-01900918 耀皮B 股上海耀华皮尔金顿玻璃股份有限公司关于国有股权无偿划转过户完成的公告本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述或者重大遗漏，并对其内容的真实性、准确性和完整性承担个别及连带责任。本公司接到中国证券登记结算有限责任公司上海分公司过户登记确认书，上海耀华玻璃厂所持本公司计117,997,072 股国有法人股无偿划转给上海建材（集团）总公司的过户手续已经办理完成。过户完成后本公司总股本仍为731,250,082，其中上海建筑材料（集团）总公司持有192,505,795 股，占本公司总股本的26.33%，成为公司第一大股东。上述权益变动的具体情况详见《上海耀华皮尔金顿玻璃股份有限公司详式权益变动报告书》和《上海耀华皮尔金顿玻璃股份有限公司简式权益变动报告书》。特此公告上海耀华皮尔金顿玻璃股份有限公司董事会2011 年1 月21 日新手上路成长任务编辑入门编辑规则本人编辑我有疑问内容质疑在线客服官方贴吧意见反馈投诉建议举报不良信息未通过词条申诉投诉侵权信息封禁查询与解封©2024 Baidu 使用百度前必读 | 百科协议 | 隐私政策 | 百度百科合作平台 | 京ICP证030173号 京公网安备110000020000

突触蛋白（SYP）基因 | MCE

突触蛋白（SYP）基因 | MCE

— Master of Bioactive Molecules

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Gene

SYP - synaptophysin Gene

SYP - synaptophysin Gene

基因

蛋白

疾病

相关产品

直系同源

中文名称：突触蛋白

种属: Homo sapiens

同用名: MRX96; MRXSYP; XLID96

基因 ID: 6855

|

基因类型: protein coding

关于 SYP

Cytogenetic location: Xp11.23

Genomic coordinates (GRCh38): X:49,187,815-49,200,193 (from NCBI)

This gene has 11 transcripts (splice variants), 263 orthologues, 3 paralogues and is associated with 3 phenotypes. Biased expression in brain (RPKM 226.8) and adrenal (RPKM 21.1).

功能概要

该基因编码大脑和内分泌细胞中小突触小泡的完整膜蛋白。该蛋白质还结合胆固醇，并被认为可将囊泡相关膜蛋白 2 (synaptobrevin) 直接靶向细胞内隔室。该基因的突变与 X 连锁形式的认知障碍有关。[RefSeq 提供，2017 年 7 月]

This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds Cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with an X-linked form of cognitive disability. [provided by RefSeq, Jul 2017]

SYP 基因产物(1)

mRNA

Protein

Name

NM_003179.3

NP_003170.1

synaptophysin

SYP 蛋白结构

MARVEL

MARVEL: Membrane-associating domain (22 - 221)

0

100

200

313 a.a.

蛋白主名

其他名称

synaptophysin

major synaptic vesicle protein P38

关联疾病

疾病名称

别名

Intellectual Developmental Disorder, X-Linked 96

XLID96

Mental Retardation, X-Linked 96

Mrx96

Mental Retardation, X-Linked, Type 96

Non-Syndromic X-Linked Intellectual Disability

X-Linked Non-Syndromic Intellectual Disability

Non-Specific X-Linked Mental Retardation

X-Linked Non-Specific Intellectual Disability

Central Neurocytoma

Neurocytoma

Neurolipocytoma

Neurocytoma Central

Neuroendocrine Carcinoma

Neuroendocrine Cancer

Carcinoma Neuroendocrine

Carcinoma, Neuroendocrine

Olfactory Neuroblastoma

Esthesioneuroblastoma

Asthesioneuroblastoma

Esthesioneuroepithelioma

Olfactory Esthesioneuroblastoma

Paranasal Sinus Olfactory Neuroblastoma

Esthesioneuroblastoma, Olfactory

Esthesioneuroblastoma Of Nasal Cavity

Ganglioneuroma

Merkel Cell Carcinoma

Trabecular Adenocarcinoma

Cutaneous Neuroendocrine Carcinoma

Trabecular Carcinoma

Carcinoma, Merkel Cell

Merkel Cell Cancer

Merkle Tumors

Mcc

Carcinoma Merkel Cell

Adrenal Cortical Adenoma

Adrenocortical Adenoma

Adenoma Adrenocortical

Subependymal Giant Cell Astrocytoma

Sega

Astrocytoma Subependymal Giant Cell

Subependymal Giant-Cell Astrocytoma

Ganglioglioma

Childhood Ganglioglioma

Adult Ganglioglioma

Cns Ganglioglioma

Mixed Cell Tumors Containing Both Neural Ganglionic Cells And Neural Glial Cell Components

Large Cell Carcinoma

Carcinoma, Large Cell

Carcinoma Large Cell

Endocrine Gland Cancer

Endocrine Neoplasm

Malignant Neoplasm Of Endocrine Gland

Endocrine Gland Neoplasms

Endocrine Tumor

Malignant Endocrine Tumor

Malignant Tumour Of Endocrine Gland

Neoplasm Of Endocrine Gland

Neoplasm Of Endocrine System

Neoplasm Of The Endocrine System

Carcinoma Of Endocrine Gland

Binswanger'S Disease

Multi-Infarct Dementia

Dementia Multi-Infarct

Binswanger Disease

Sertoli Cell Tumor

Tubular Androblastoma

Neuroendocrine Tumor

Neuroendocrine Neoplasm

Neuroendocrine Tumors

Carcinoma, Neuroendocrine

Pulmonary Sclerosing Hemangioma

Pneumocytoma

Sclerosing Hemangioma

Sclerosing Haemangioma

Cutaneous Fibrous Histiocytoma

Paraganglioma

Chemodectoma

Glomus Body Tumor

Paragangliomas

Carotid Body Paraganglioma

Extra-Adrenal Paraganglioma

Pineoblastoma

Pineal Pnet

Pinealoma

Pineal Gland Neoplasm

Pineocytoma

Tumor Of The Pineal Region

Glomus Tumor

Glomus Neoplasm

Glomus Tumour

Large Cell Neuroendocrine Carcinoma

Rhabdoid Cancer

Rhabdoid Tumor

Malignant Rhabdoid Tumor

Malignant Rhabdoid Tumour

Rhabdoid Sarcoma

Rhabdoid Tumor Predisposition Syndrome 1

Rhabdoid Tumor Predisposition Syndrome 2

Atypical Teratoid Rhabdoid Tumor

Brain Tumor, Posterior Fossa, Of Infancy, Familial

Atypical Teratoid/Rhabdoid Tumor

Blastoma

Embryoma

Malignant Olfactory Nerve Neoplasm

Malignant Olfactory Nerve Tumor

Malignant Tumor Of Olfactory Nerve

Primary Malignant Neoplasm Of Olfactory Nerve

Nasal Cavity Cancer

Nasal Cavity Carcinoma

Malignant Neoplasm Of Nasal Cavities

Malignant Tumor Of The Nasal Cavity

Cancer Of Nasal Cavity

Carcinoma Of Nasal Cavity

Malignant Neoplasm Of Nasal Cavity

Neoplasm Of Nasal Cavity

Ganglioneuroblastoma

Hemangioblastoma

Capillary Hemangioblastoma

Pineocytoma

Pinealoma

Pinealocytoma

Pineal Gland Neoplasm

Tumor Of The Pineal Region

Middle Ear Adenoma

Adenoma Of Middle Ear

Adenoma Of The Middle Ear

Auditory System Benign Neoplasm

Neurofibroma

Neurofibromas

Neurofibromatoses

Nerve Sheath Tumors

Oligodendroglioma

Oligodendroglial Neoplasm

Oligodendroglial Tumor

Oligodendroglial Tumors

Well Differentiated Oligodendroglioma

Breast Neuroendocrine Neoplasm

Neuroendocrine Tumor Of The Breast

Sensory Organ Benign Neoplasm

Pulmonary Large Cell Neuroendocrine Carcinoma

Large Cell Lung Neuroendocrine Carcinoma

Cerebral Neuroblastoma

Neuroblastoma Of Brain

Neuroblastoma Of Cerebrum

Neuroblastoma Of The Cerebral Hemisphere

Papillary Ependymoma

Ependymoma Papillary

Pulmonary Blastoma

Blastoma Of Lung

Pneumoblastoma

Lung Large Cell Carcinoma

Large Cell Carcinoma Of Lung

Large Cell Lung Carcinoma

Large Cell Lung Cancer

Esophageal Neuroendocrine Tumor

Esophageal Neuroendocrine Tumour

Neuroendocrine Tumor Of Esophagus

Neuroendocrine Tumour Of Oesophagus

Urinary Bladder Small Cell Neuroendocrine Carcinoma

Small Cell Neuroendocrine Carcinoma Of The Urinary Bladder

Small Cell/Neuroendocrine Carcinoma Of Urinary Bladder

Benign Teratoma

Dermoid Cyst

Cystic Dermoid Choristoma

Dermoid Choristoma

Mature Cystic Teratoma

Dermoid Tumour

Teratoma, Benign

Dermoid Cyst Of Ovary

Ampulla Of Vater Benign Neoplasm

Tumor Of The Ampulla Of Vater

Ureter Small Cell Carcinoma

Ureteral Small Cell Carcinoma

Papilloma Of Choroid Plexus

Choroid Plexus Papilloma

CPP

Childhood Choroid Plexus Papilloma

Papilloma Choroid Plexus

Papilloma, Choroid Plexus

Choroid Plexus Carcinoma

Duodenal Benign Neoplasm

Neoplasm Of Duodenum

Neoplasm Of The Duodenum

Cancer Of Duodenum

Ovarian Large-Cell Neuroendocrine Carcinoma

Non-Small-Cell Type Neuroendocrine Carcinoma Of Ovary

Ovarian Large Cell Neuroendocrine Carcinoma

Bladder Small Cell Carcinoma

Small Cell Bladder Cancer

Small Cell Carcinoma Of The Bladder

Poorly Differentiated Neuroendocrine Carcinoma Of The Bladder

Sccb

Small Cell Bladder Carcinoma

Small Cell Carcinoma Of The Urinary Bladder

Tuberous Sclerosis

Tuberous Sclerosis Syndrome

Bourneville'S Disease

Epiloia

Cerebral Sclerosis

Tuberose Sclerosis

Tuberous Sclerosis 1

Bourneville Disease

Bourneville Phakomatosis

Pringle'S Disease

Cranial Nerve Malignant Neoplasm

Cranial Nerve Neoplasms

Malignant Neoplasm Of Cranial Nerve

Malignant Tumor Of Cranial Nerve

Malignant Tumor Of The Cranial Nerve

Cellular Ependymoma

Ependymoma

Classic Ependymoma

Papillary Ependymoma

Tanycytic Ependymoma

Clear Cell Ependymoma

Ependymoma, Familial

Epithelial Ependymoma

Who Grade Ii Ependymal Neoplasm

Ovarian Mucinous Adenofibroma

Ovarian Mucinous Cystadenofibroma

Sertoli-Leydig Cell Tumor

Sertoli-Leydig Cell Tumors

Androblastoma Of Ovary

Arrhenoblastoma

Arrhenoblastoma Of Ovary

Sertoli-Leydig Cell Tumor Of The Ovary

Sertoli-Leydig Cell Tumor Of Intermediate Differentiation

Sertoli-Leydig Cell Tumor Of Ovary

Sweat Gland Cancer

Sweat Gland Carcinoma

Malignant Neoplasm Of Sweat Gland

Malignant Tumor Of The Sweat Gland

Carcinoma Of The Sweat Gland

Primary Malignant Neoplasm Of Sweat Gland

Sweat Gland Neoplasms

Pheochromocytoma

Pheochromocytoma, Susceptibility To

Phaeochromocytoma

Adrenal Gland Chromaffin Paraganglioma

Adrenal Gland Chromaffinoma

Adrenal Gland Paraganglioma

Adrenal Gland Pheochromocytoma

Chromaffin Paraganglioma Of The Adrenal Gland

Intraadrenal Paraganglioma

PCC

Chromaffin Cell Tumor

Medullary Chromaffinoma

Medullary Paraganglioma

Pheochromoblastoma

Pheochromocytomas

Chromaffin Cell Neoplasm

Pheochromocytoma, Malignant

Pineal Gland Cancer

Tumor Of The Pineal Region

Malignant Pineal Region Tumor

Malignant Tumor Of Pineal Gland

Neoplasm Of Pineal Gland

Neoplasm Of The Pineal Region

Pineal Body Neoplasm

Pineocytic Tumor

Malignant Neoplasm Of Pineal Gland

Pineal Gland Neoplasm

Pineocytoma

Basaloid Squamous Cell Carcinoma

Basaloid Carcinoma

Melanotic Neuroectodermal Tumor

Melanotic Neuroectodermal Tumor Of Infancy

Neuroectodermal Tumor, Melanotic

Infantile Melanotic Neuroectodermal Neoplasm

Melanotic Neuroectodermal Tumour

Melanotic Neuroectodermal Tumour Of Infancy

Pigmented Neuroectodermal Tumour Of Infancy

Pulmonary Neuroendocrine Tumor

Neuroendocrine Neoplasm Of Lung

Thymic Carcinoma

Malignant Thymoma

Thymoma, Malignant

Supratentorial Cancer

Supratentorial Neoplasms

Brain Neoplasm, Supratentorial

Malignant Supratentorial Tumor

Cancer, Supratentorial

Cerebrum Cancer

Cerebral Cancer

Neoplasm Of Cerebrum

Tumor Of Cerebrum

Malignant Neoplasm Of Cerebrum

Cerebellar Liponeurocytoma

Lipomatous Medulloblastoma

Central Neurocytoma

Islet Cell Tumor

Pancreatic Neuroendocrine Tumor

Neuroendocrine Tumor Of Pancreas

Pnet

Pancreatic Net

Pancreatic Endocrine Tumor

Well-Differentiated Nen Of Pancreas

Well-Differentiated Neuroendocrine Neoplasm Of Pancreas

Well-Differentiated Pancreatic Nen

Well-Differentiated Pancreatic Neuroendocrine Neoplasm

Endocrine Pancreas Cancer

Islet Cell Neoplasm

Islet Cell Tumour

Malignant Pancreatic Endocrine Tumor

Malignant Pancreatic Endocrine Tumour

Malignant Tumor Of Endocrine Pancreas

Malignant Tumour Of Endocrine Pancreas

Pancreatic Endocrine Neoplasm

Pancreatic Neuroendocrine Neoplasm

Adenoma, Islet Cell

Well Differentiated Pancreatic Endocrine Tumor

Malignant Neoplasm Of Endocrine Pancreas

Pancreatic Endocrine Carcinoma

Medullomyoblastoma

Breast Papillary Carcinoma

Breast Solid Papillary Carcinoma

Papillary Carcinoma Of Breast

Papillary Carcinoma Of The Breast

Solid Papillary Carcinoma Of The Breast

Pineal Parenchymal Tumor Of Intermediate Differentiation

Pineal Parenchymal Tumour Of Intermediate Differentiation

Pineal Parenchymal Tumors Of Intermediate Differentiation

Pptid

Auditory System Cancer

Ear Neoplasms

Carcinoid Tumors, Intestinal

Carcinoid

Gastrointestinal Carcinoid Tumor

Argentaffinoma

Intestinal Carcinoid Tumor

ICT

Tumor, Carcinoid, Intestinal

Malignant Carcinoid Syndrome

Carcinoid Tumor Of Intestine

Carcinoid Tumor

Carcinoid Tumor No Icd-O Subtype

Small Cell Cancer Of The Lung

Small Cell Lung Cancer

Small Cell Lung Carcinoma

Sclc

Small-Cell Cancer Of Lung

Lung Small Cell Carcinoma

Sclc1

Sccl

Cancer, Lung, Small Cell

Small Cell Carcinoma Of Lung

Carcinoma, Small Cell

Mixed Ductal-Endocrine Carcinoma

Carotid Body Cancer

Cancer Of Carotid Body

Malignant Carotid Body Paraganglioma

Malignant Carotid Body Tumor

Malignant Neoplasm Of Carotid Body

Gangliocytoma

Ganglioneuroma

Gangliocytoma Of Central Nervous System

Gastrointestinal Neuroendocrine Tumor

Gastrointestinal Neuroendocrine Tumour

Malignant Gastrointestinal Neuroendocrine Tumor

Malignant Gastrointestinal Neuroendocrine Tumour

Digestive System Neuroendocrine Neoplasm

Digestive System Neuroendocrine Tumor

Obstructive Hydrocephalus

Endometrial Small Cell Carcinoma

Sinonasal Undifferentiated Carcinoma

Highly Aggressive Undifferentiated Carcinoma Of The Nasal Cavity And Paranasal Sinuses

Snuc

Pancreatoblastoma

Cauda Equina Neoplasm

Tumor Of The Cauda Equina

Neoplasm Of Cauda Equina

Cerebral Ventricle Cancer

Cerebral Ventricle Neoplasms

Cerebral Ventricle Neoplasm

Intraventricular Tumor Of Brain

Paranasal Sinus Cancer

Paranasal Sinus Adenoid Cystic Carcinoma

Paranasal Sinus Mucoepidermoid Carcinoma

Paranasal Sinus Squamous Cell Carcinoma

Paranasal Sinus Neoplasms

Adenoid Cystic Carcinoma Of Accessory Sinus

Adenoid Cystic Carcinoma Of Paranasal Sinus

Epidermoid Carcinoma Of The Paranasal Sinus

Mucoepidermoid Carcinoma Of Accessory Sinus

Paranasal Sinus Adenocarcinoma

Squamous Cell Carcinoma Of Paranasal Sinus

Paranasal Sinus Neoplasm

Adenocarcinoma Of Accessory Sinus

Gallbladder Small Cell Carcinoma

Oat Cell Carcinoma Of The Gallbladder

Gallbladder Small Cell Neuroendocrine Carcinoma

Colon Neuroendocrine Neoplasm

Colonic Neuroendocrine Tumor

Creutzfeldt-Jakob Disease

Variant Creutzfeldt-Jakob Disease

CJD

Bovine Spongiform Encephalopathy

Vcjd

Inherited Creutzfeldt-Jakob Disease

Creutzfeldt-Jakob Disease, Familial

Creutzfeldt Jakob Disease

Creutzfeldt-Jacob Disease

Creutzfeldt Jacob Disease

Sporadic Creutzfeldt-Jakob Disease

Encephalopathy, Bovine Spongiform

Creutzfeldt-Jakob Disease, Variant, Resistance To

Creutzfeldt-Jakob Disease, Variant

Creutzfeldt Jacob Syndrome

Jakob-Creutzfeldt Disease

Subacute Spongiform Encephalopathy

Transmissible Virus Dementia

New Variant Of Cjd

Nv-Cjd

Variant Cjd

Variant Creutzfeldt-Jacob Disease

Sporadic Cjd

Inherited Cjd

Acquired Creutzfeldt-Jakob Disease

Variant Mcj

Encephalopathy Bovine Spongiform

Familial Creutzfeldt-Jakob Disease

Creutzfeldt-Jakob Syndrome

New Variant Creutzfeldt-Jakob Disease

Creutzfeldt-Jakob Disease, Sporadic

Acquired Cjd

Scjd - [Sporadic Creutzfeldt-Jakob Disease]

Idiopathic Creutzfeldt-Jakob Disease

Creutzfeld-Jakob Disease Nos

Vcjd - [Variant Creutzfeldt-Jakob Disease]

Cystadenoma

Cystoma

Craniopharyngioma

Gastric Small Cell Carcinoma

Small Cell Carcinoma Of Stomach

Spinal Muscular Atrophy, Type I

Werdnig-Hoffmann Disease

SMA1

Spinal Muscular Atrophy 1

Sma I

Sma, Infantile Acute Form

Muscular Atrophy, Infantile

Spinal Muscular Atrophy-1

Hmn Proximal Type I

Infantile Muscular Atrophy

Proximal Spinal Muscular Atrophy Type 1

Sma Type 1

Sma Type I

Sma-I

Hereditary Motor Neuropathy Proximal Type I

Progressive Muscular Atrophy Of Infancy

Proximal Spinal Muscular Atrophy, Type 1

Werdnig Hoffmann Disease

Infantile Spinal Muscular Atrophy

Infantile-Onset Spinal Muscular Atrophy

Proximal Hereditary Motor Neuropathy Type I

Sma Infantile Acute Form

Spinal Muscular Atrophy Type I

Werdnig-Hoffman Disease

Atrophy, Muscular, Spinal, Type 1

Acinar Cell Cystadenocarcinoma

Pancreatic Acinar Cell Cystadenocarcinoma

Leydig Cell Tumor

Leydig Cell Neoplasm

Tumor, Leydig Cell

Leydig Cell Tumor, Benign

Adrenal Carcinoma

Adrenal Cancer

Adrenal Gland Cancer

Malignant Neoplasm Of Adrenal Gland

Adrenal Gland Neoplasms

Carcinoma Of The Adrenal Gland

Adrenal Neoplasm

Malignant Adrenal Tumor

Neoplasm Of Adrenal Gland

Tumor Of The Adrenal Gland

Adrenal Gland Neoplasm

Adrenocortical Carcinoma

Adrenal Gland Malignancy

Suprarenal Cancer

Malignant Neoplasm Of Suprarenal Gland

Malignant Neoplasm Of Adrenal Gland, Unspecified

Malignant Tumour Of Adrenal Gland

Suprarenal Gland Cancer

Primary Malignant Neoplasm Of Adrenal Gland

Lung Benign Neoplasm

Lung Neoplasms

Tumor Of The Lung

Lung Tumor

Cervix Small Cell Carcinoma

Small Cell Carcinoma Of The Cervix

Small Cell Carcinoma Of The Cervix Uteri

Medulloblastoma

MDB

Cpnet

Localized Primitive Neuroectodermal Tumor

Classic Medulloblastoma

Medulloblastoma Predisposition Syndrome

Medulloblastoma, Somatic

Brain Medulloblastoma

Cns Pnet

Infratentorial Primitive Neuroectodermal Tumor

Neuroectodermal Tumors, Primitive

Medulloblastomas

Desmoplastic Medulloblastoma

Medulloblastoma, With Extensive Nodularity

Medulloblastoma Of Unspecified Site

Medullomyoblastoma Of Unspecified Site

Pancreatic Acinar Cell Adenocarcinoma

Pancreatic Acinar Cell Carcinoma

Acinar Cell Adenocarcinoma Of The Pancreas

Appendix Carcinoid Tumor

Appendix Carcinoid Endocrine Tumour

Carcinoid Tumor Of Appendix

Medulloepithelioma

Diktyoma, Malignant

Medulloepithelioma, Central Nervous System

Medulloepithelioma Of The Central Nervous System

Granular Cell Tumor

Abrikosov'S Tumor

Neoplasm Of Granular Cell

Abrikosoff'S Granulous Cell Tumor

Abrikosoff'S Tumor

Giant Granulocellular Abrikosov'S Tumor

Malignant Variant Of Abrikosov'S Tumor

Carcinoma, Granular Cell

Mediastinal Cancer

Mediastinal Neoplasms

Mediastinal Tumor

Mediastinum Cancer

Neoplasm Of Mediastinum

Tumour Of Mediastinum

Malignant Tumor Of Mediastinum

Glomangiosarcoma

Malignant Glomus Neoplasm

Glomus Tumor, Malignant

Pilocytic Astrocytoma

Juvenile Pilocytic Astrocytoma

Grade I Astrocytic Tumor

Piloid Astrocytoma

Peripheral Nervous System Benign Neoplasm

Autonomic Nervous System Benign Neoplasm

Teratoma

Teratomas

Amyloidosis

Amyloid Disease

Amyloid

Amyloid Degeneration

Amyloidosis Nos

Amyloid Deposition

Amyloid Infiltration

Idiopathic Amyloidosis

Hyaloid Degeneration

Lardaceous Degeneration

Tubular Adenocarcinoma

Tubular Carcinoma

Adenocarcinoma Tubular

Adenocarcinoma, Tubular

Adrenal Neuroblastoma

Neuroblastoma Of Adrenal Gland

Adrenal Gland Neuroblastoma

Neuroblastoma Nos

Cerebrovascular Benign Neoplasm

Benign Perivascular Tumor

Benign Pericytic Neoplasm

Ovarian Germ Cell Teratoma

Germ Cell Teratoma Of Ovary

Ovarian Teratoma

Central Nervous System Primitive Neuroectodermal Neoplasm

Cpnet

Glomangioma

Malignant Melanocytic Neoplasm Of The Peripheral Nerve Sheath

Melanotic Malignant Nerve Sheath Tumor

Melanocytic Mpnst

Melanotic Malignant Peripheral Nerve Sheath Tumor

Melanotic Malignant Peripheral Nerve Sheath Tumour

Adenoma

Acinar Cell Adenoma

Adenomas

Acinic Cell Adenoma

Glomangiomyoma

Gastrointestinal Neuroendocrine Benign Tumor

Gastrinoma

Gastrin Cell Tumour

Gastrin Secreting Tumor

Malignant Gastrinoma

Gastrinoma, Malignant

Multiple Endocrine Neoplasia

Men

Multiple Endocrine Adenomatosis

Multiple Endocrine Neoplasia Syndrome

Adenomatosis, Familial Endocrine

Endocrine Neoplasia, Multiple

Familial Endocrine Adenomatosis

Mea

Multiple Endocrine Neoplasms

Multiple Endocrine Neoplasia Type 1

Spinal Cord Oligodendroglioma

Oligodendroglioma Of Spinal Cord

Well Differentiated Spinal Cord Oligodendroglioma

Extraosseous Ewing Sarcoma

Extraosseous Ewing'S Sarcoma

Extraosseous Ewing'S Sarcoma/Peripheral Primitive Neuroectodermal Tumor

Extraskeletal Ewing Sarcom

Sarcoma Extraosseous Ewings

Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor

Conn'S Syndrome

Cushing Syndrome

Hyperaldosteronism

Primary Hyperaldosteronism

Hypercortisolism

Primary Aldosteronism

Cushing'S Syndrome

Adrenal Gland Hyperfunction

Conn Syndrome

Hyperadrenalism

Ectopic Acth Syndrome

Hyperadrenocorticism

Cushing Disease

Cushing'S Disease

Adrenal Cortex Adenoma

Corticotroph Pituitary Adenoma

Pituitary Corticotroph Micro-Adenoma

Pituitary-Dependent Cushing Syndrome

Pituitary Acth Hypersecretion

Acth Syndrome, Ectopic

Acth-Secreting Pituitary Adenoma

Adrenal Hyperfunction Resulting From Pituitary Acth Excess

Ectopic Adrenocorticotropic Hormone Syndrome

Nodular Primary Adrenocortical Dysplasia

Pituitary Dependent Cushing Syndrome

Pituitary Cushing Syndrome

Pituitary-Dependant Cushing Syndrome

Pituitary-Dependant Hypercortisolism

Pituitary-Dependant Hypercortisolism Disorder

Aldosteronism Primary

Acth Syndrome Ectopic

Adrenal Cushing'S Syndrome

Adrenal Cortical Adenoma

Cushing Syndrome Nos

Cortisol Hypersecretion

Corticoadrenal Hypersecretion

Cushing Syndrome Secondary To Ectopic Acth-Secretion

Ectopic Cushing Syndrome

Hypercortisolism Due To Nonpituitary Tumour

Ectopic Acth - [Adrenocorticotropic Hormone] Secretion

Ectopic Acth - [Adrenocorticotropic Hormone] Secretion Causing Cushing Syndrome

Idiopathic Aldosteronism

Aldosteronism

Primary Aldosteronism Due To Bilateral Adrenal Hyperplasia

Primary Aldosteronism Due To Adrenal Hyperplasia

Ovary Neuroendocrine Neoplasm

Neuroendocrine Tumor Of Ovary

Laryngeal Small Cell Carcinoma

Small Cell Carcinoma Of Larynx

Choroid Plexus Cancer

Choroid Plexus Carcinoma

Choroid Plexus Neoplasms

Choroid Plexus Neoplasm

Tumor Of Choroid Plexus

Tumor Of The Choroid Plexus

Choroid Plexus Tumor

Choroid Plexus Tumors

Anaplastic Choroid Plexus Papilloma

Choroid Plexus Papilloma Nos

Papilloma Of Choroid Plexus

Plexus Choroideus Papilloma

Choroid Plexus Papilloma In Fourth Ventricle

Plexus Choroideus Papilloma In Fourth Ventricle

Dysembryoplastic Neuroepithelial Tumor

Dysembryoplastic Neuroepithelial Tumour

Dysembryoplastic Neuroepithelial Neoplasm

Dnet

Chordoid Meningioma

Meningioma, Chordoid

Carcinosarcoma

Mixed Tumor, Mullerian

Malignant Mixed Mesodermal Tumor

Malignant Mixed Mullerian Tumor

Mmmt

Mixed Tumor, Mesodermal

Mesodermal Mixed Tumor

Mixed Mesodermal Tumor

Mullerian Mixed Tumor

Mixed Mullerian Tumor

Malignant Mixed Müllerian Tumor

Mixed Müllerian Tumor

Mixed Tumor Mullerian

Mixed Tumor, Not Otherwise Specified

Vagus Nerve Neoplasm

Neoplasm Of Vagus Nerve

Vagus Nerve Tumors

Anal Neuroendocrine Tumor

Anal Neuroendocrine Tumour

Neuroendocrine Tumor Of Anus

Neuroendocrine Tumour Of Anus

Anal Canal Neuroendocrine Tumor

Hemangioma

Hemangiomas

Adrenal Cortical Carcinoma

Adrenocortical Carcinoma

Adrenal Cortex Carcinoma

Carcinoma Of The Adrenal Cortex

Acc

Adrenocortical Cancer

Carcinoma Adrenocortical

Thymus Small Cell Carcinoma

Small Cell Carcinoma Of The Thymus

Thymic Small Cell Carcinoma

Small Cell Carcinoma

Small Cell Carcinoma, Intermediate Cell

Intermediate Cell Small Cell Carcinoma

Small Cell Carcinoma - Intermediate Cell

Small Cell Carcinoma Of Lung

Carcinoma, Small Cell

Prostate Neuroendocrine Neoplasm

Neuroendocrine Tumor Of The Prostate

Intestinal Pseudo-Obstruction

Chronic Intestinal Pseudoobstruction

Chronic Intestinal Pseudo-Obstruction

Cipo

Neuronal Intestinal Dysplasia

Hollow Visceral Myopathy

Familial Visceral Neuropathy

Paralytic Ileus

Intestinal Pseudoobstruction

Chronic Idiopathic Intestinal Pseudo-Obstruction

Ciip

Congenital Short Bowel Syndrome

Enteric Neuropathy

Familial Visceral Myopathy

Ipo

Pseudo-Obstruction Of Intestine

Pseudointestinal Obstruction Syndrome

Pseudoobstructive Syndrome

Congenital Idiopathic Intestinal Pseudoobstruction

Visceral Myopathy, Familial

Cystic Teratoma

Dermoid Cyst

Benign Teratoma

Neuronal Intestinal Dysplasia, Type B

Neuronal Intestinal Dysplasia Type B

Nid B

Gastrointestinal Stromal Tumor

GIST

Gastrointestinal Stromal Tumors

Gastrointestinal Stromal Sarcoma

Gastrointestinal Stromal Tumor, Familial

Gant

Gastrointestinal Stromal Tumour

Stromal Tumor Of Gastrointestinal Tract

Stromal Tumour Of Gastrointestinal Tract

Gastrointestinal Stromal Neoplasm

Paraganglioma And Gastric Stromal Sarcoma

Plexosarcoma

Cerebellum Cancer

Cerebellar Neoplasms

Cerebellar Cancer

Malignant Tumor Of Cerebellum

Malignant Neoplasm Of Cerebellum

Lung Cancer

Lung Carcinoma

Non-Small Cell Lung Carcinoma

Lung Cancer, Susceptibility To

Lung Cancer, Protection Against

Adenocarcinoma Of Lung, Somatic

Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In

Nonsmall Cell Lung Cancer

Lung Neoplasm

Carcinoma Of Lung

Lung Non-Small Cell Carcinoma

Non-Small Cell Lung Cancer

Nsclc

Lung Neoplasms

Malignant Neoplasm Of Lung

Alveolar Cell Carcinoma

Nonsmall Cell Lung Cancer, Somatic

Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In

Nonsmall Cell Lung Cancer, Susceptibility To

Lung Cancer, Somatic

Lung Cancer, Resistance To

Cancer Of Lung

Cancer Of Bronchus

Cancer Of The Lung

Lung Malignancies

Lung Malignant Tumors

Malignant Lung Tumor

Malignant Tumor Of Lung

Pulmonary Cancer

Pulmonary Carcinoma

Pulmonary Neoplasms

Respiratory Carcinoma

LNCR

Adenocarcinoma Of Lung

Neoplasm Of Lung

Cancer Lung

Carcinoma Non-Small Cell Lung

Carcinoma, Non-Small-Cell Lung

Lung Cancers

Lung Carcinomas

Cancer, Lung

Cancer, Lung, Non-Small Cell

Primary Malignant Neoplasm Of Lung

Bronchioloalveolar Adenocarcinoma

Supratentorial Primitive Neuroectodermal Tumor

Supratentorial Pnet

Supratentorial Embryonal Tumor, Not Otherwise Specified

Ewings Sarcoma-Primitive Neuroectodermal Tumor

Glomangiomatosis

Askin'S Tumor

Askin Tumor

Askin Tumour

Askin'S Tumour

Clear Cell Ependymoma

Cellular Ependymoma

Brain Cancer

Adult Brain Tumor

Malignant Neoplasm Of Brain

Brain Neoplasms

Brain Neoplasm

Neoplasm Of Brain

Primary Malignant Neoplasm Of Brain

Brain Tumors

Adult Malignant Brain Neoplasm

Brain Neoplasm, Adult

Bt - Brain Tumour

Malignant Brain Tumour

Malignant Primary Brain Neoplasm

Malignant Primary Brain Tumor

Malignant Tumor Of Adult Brain

Malignant Tumor Of Brain

Primary Brain Neoplasm

Primary Brain Tumor

Tumor Of The Brain

Brain Tumor, Adult

Brain Tumor Primary

Malignant Primary Brain Tumors

Primary Brain Tumors

Cancer, Brain

Brain Tumor, Primary

Microcystic Adenoma

Adenoma Microcystic

Adenoma, Microcystic

Adrenogenital Syndrome

Adrenogenital Disease

Adrenogenital Syndrome Nos

Gastric Neuroendocrine Neoplasm

Gastric Neuroendocrine Tumor

Neuroendocrine Tumor Of The Stomach

Neuroendocrine Tumor Of Stomach

Gnet

Gastric Net

Net Of Stomach

Mucinous Adenofibroma

Cervical Large Cell Neuroendocrine Carcinoma

Cloacogenic Carcinoma

Cloacogenic Anal Carcinoma

Myocardium Cancer

Malignant Myocardial Tumor

Malignant Neoplasm Of Myocardium

Tumor Of Myocardium

Malignant Tumor Of Myocardium

Embryonal Tumor With Multilayered Rosettes, C19mc-Altered

Ependymoblastoma

Hirschsprung Disease 1

Hirschsprung Disease

Aganglionic Megacolon

Hscr

Hirschsprung'S Disease

Congenital Megacolon

Congenital Intestinal Aganglionosis

Colonic Aganglionosis

Hirschsprung Disease, Susceptibility To, 1

Hirschsprung Disease, Protection Against

HSCR1

Mgc

Pelvirectal Achalasia

Total Intestinal Aganglionosis

Megacolon, Aganglionic

Macrocolon

Hscr 1

Hirschsprung Disease Type 1

Hirschsprung Disease, Type 1

Congenital Dilatation Of Colon

Aganglionosis

Congenital Aganglionic Megacolon

Aganglionosis Of Colon

Bowel Aganglionosis

Colon Aganglionosis

Hirschsprung Megacolon

Laryngeal Neuroendocrine Tumor

Laryngeal Neuroendocrine Tumour

Neuroendocrine Tumor Of Larynx

Neuroendocrine Tumour Of Larynx

Neuroendocrine Neoplasm Of Larynx

Papillary Squamous Carcinoma

Papillary Epidermoid Carcinoma

Papillary Squamous Cell Carcinoma

Chiari Malformation

Dementia

Dementias

Presenile Dementia

Alzheimer Type Dementia

Alzheimer Sclerosis

Alzheimer Disease Dementia

Alzheimer Dementia

Primary Degenerative Alzheimer Type Dementia

End Stage Alzheimer'S Dementia

Alzheimer'S Type Atypical Dementia

Alzheimer Type Presenile Dementia

Early Onset Alzheimer Dementia

Dementia In Alzheimer Disease Type 2

Dementia In Alzheimer Disease With Early Onset

Early Onset Alzheimer Type Dementia, Uncomplicated

Primary Degenerative Alzheimer Type Dementia, Early Onset

Primary Degenerative Alzheimer Type Dementia, Presenile Onset, Uncomplicated

Alzheimer Disease Dementia With Early Onset

Presenile Sclerosis

Presenile Brain Sclerosis

Presenile Alzheimer Brain Sclerosis

Late Onset Alzheimer Dementia

Dementia In Alzheimer Disease Type 1

Dementia In Alzheimer Disease With Late Onset

Primary Degenerative Alzheimer Type Dementia, Late Onset

Sdat - [Senile Dementia, Alzheimer Type]

Alzheimer Disease Dementia With Late Onset

Late Onset Alzheimer Brain Sclerosis

Senile Alzheimer Brain Disease

Senile Alzheimer Brain Sclerosis

Senile Primary Degenerative Alzheimer Type Dementia

Senile Dementia Of The Alzheimer Type

Arteriosclerotic Dementia

Strategic-Infarct Dementia

Post Stroke Dementia

Vascular Cognitive Impairment

Vascular Dementia

Dementia Of The Lewy Body Type

Dementia With Lewy Bodies

Sdlt - [Senile Dementia Of The Lewy Body Type]

Senile Dementia Of The Lewy Body Type

Alcohol-Related Dementia

Alcoholic Dementia Nos

Alcohol-Induced Dementia

Alcoholic Brain Syndrome

Chronic Alcoholic Brain Syndrome

Alcohol Dementia

Late Onset Alcoholic Psychosis

Residual And Late-Onset Alcohol-Induced Psychotic Disorder

Mental And Behavioural Disorders Due To Use Of Sedatives Or Hypnotics, Residual And Late-Onset Psychotic Disorder

Late-Onset Psychoactive Substance-Induced Psychotic Disorder

Inhalant Dementia

Volatile Solvents Dementia

Dementia In Paralysis Agitans

Pdd - [Parkinson Disease Dementia]

Dementia Syndrome Of Parkinson Disease

Dementia In Parkinson Disease

Parkinson Related Dementia

Dementia In Huntington Chorea

Hiv - [Human Immunodeficiency Virus] Dementia

Hiv- [Human Immunodeficiency Virus] Associated Cognitive Motor Complex

Hiv- [Human Immunodeficiency Virus] Associated Dementia Complex

Aids - [Acquired Immunodeficiency Syndrome] Dementia Complex

Aids Related Dementia

Dementia Due To Niacin Deficiency

Extra-Adrenal Pheochromocytoma

Pheochromocytoma, Extra-Adrenal

Perivascular Tumor

Malignant Perivascular Cancer

Carcinoid Syndrome

Carcinoid Tumor

Malignant Carcinoid Syndrome

Carcinoid Tumor Syndrome

Carcinoid Tumors

Carcinoid Tumor No Icd-O Subtype

Argentaffinoma Syndrome

Hydrocephalus

Hydrocephalus, Nonsyndromic, Autosomal Recessive

Hydrocephalus, X-Linked

Hydrocephalus Adverse Event

Hydrocephaly Nos

Malignant Teratoma

Immature Teratoma

Malignant Extragonadal Teratoma

Primary Malignant Extragonadal Teratoma

Teratoma, Malignant, Nos

Teratoma, Malignant

Immature Extragonadal Teratoma

Lung Meningioma

Lung Primary Meningioma

Primary Pulmonary Meningioma

Pulmonary Meningioma

Primary Lung Meningioma

Oncocytoma

Oxyphilic Adenoma

Follicular Adenoma, Oxyphilic Cell

Adenoma, Oxyphilic

Hurthle Cell Tumor

Oncocytic Neoplasm

Extraosseous Chondrosarcoma

Extraskeletal Myxoid Chondrosarcoma

Partial Cryptophthalmia

Incomplete Cryptophthalmos

Jejunal Neoplasm

Jejunal Tumor

Neoplasm Of Jejunum

Tumor Of Jejunum

Rhabdoid Meningioma

Papillary Meningioma

Meningioma, Rhabdoid

Small Intestine Benign Neoplasm

Neoplasm Of Small Intestine

Small Intestinal Neoplasm

Neoplasm Of The Small Intestine

Small Bowel Cancer

Small Intestine Cancer

Malignant Neoplasm Of Small Intestine, Unspecified

Malignant Tumour Of Small Bowel

Malignant Tumour Of Small Intestine

Primary Malignant Neoplasm Of Meckel Diverticulum

Benign Ependymoma

Ependymoma

Epithelial Ependymoma

Who Grade Ii Ependymal Tumor

Myxopapillary Ependymoma

Ectomesenchymoma

Rhabdomyosarcoma With Ganglionic Differentiation

Malignant Ectomesenchymoma

Thymoma

Primary Thymic Epithelial Neoplasm

Primary Thymic Epithelial Tumor

Thymus Neoplasms

Krukenberg Carcinoma

Krukenberg Tumor

Krukenberg Neoplasm

Krukenberg'S Tumor

Central Nervous System Mesenchymal Non-Meningothelial Tumor

Central Nervous System Mesenchymal Non-Meningothelial Tumour

Non-Meningothelial Mesenchymal Tumor

Non-Meningothelial Mesenchymal Tumour

Nodular Ganglioneuroblastoma

Ganglioneuroblastoma, Nodular

Motor Neuron Disease

Anterior Horn Cell Disease

Motor Neuron Diseases

Mnd - [Motor Neurone Disease]

Lou Gehrig Disease

Creeping Palsy

Creeping Paralysis

Bulbar Motor Neuron Disease

Bulbar Syndrome

Anterior Horn Cell Disorder

Hereditary Motor Neuron Disease

Malignant Pheochromocytoma

Pheochromocytoma, Malignant

Atypical Teratoid Rhabdoid Tumor

Rhabdoid Tumor Predisposition Syndrome

Rtps

Atypical Teratoid/Rhabdoid Tumor

Rhabdoid Predisposition Syndrome

Familial Posterior Fossa Brain Tumor Of Infancy

Familial Rhabdoid Tumor

At/Rt

Atypical Teratoid Rhabdoid Tumour

Atypical Teratoid/Rhabdoid Tumour

Rhabdoid Tumor Of The Cns

Rhabdoid Tumour Of The Cns

Familial Posterior Fossa Brain Tumor Syndrome

Hereditary Swi/Snf Deficiency Syndrome

Atrt

Adrenal Medulla Cancer

Adrenal Medulla Neoplasm

Adrenal Medulla Tumor

Malignant Neoplasm Of Adrenal Medulla

Malignant Tumor Of The Adrenal Medulla

Adrenal Medulla Carcinoma

Neoplasm Of Adrenal Medulla

Meningioma, Familial

Meningioma

Familial Meningioma

Meningioma, Familial, Susceptibility To

Meningeal Neoplasm

Meningeal Neoplasms

Meningiomas

Meningioma, Nf2-Related, Somatic

Meningioma, Sis-Related

Meningothelial Cell Tumor

Neoplasm Of The Meninges

Primary Meningeal Tumor

Familial Multiple Meningioma

MNGMA

Meningioma, Benign, No Icd-O Subtype

Intracranial Meningioma

Meningothelial Cell Neoplasm

Supratentorial Meningioma

Primary Neoplasm Of Spinal Meninges

Benign Intracranial Meningioma

Benign Meningioma

Meningeal Tumours

Meningeal Sarcoma Of Unspecified Site

Meningothelial Sarcoma Of Unspecified Site

Lung Oat Cell Carcinoma

Oat Cell Carcinoma

Carcinoma Oat Cell

Carcinoma, Small Cell

Mixed Cell Type Cancer

Malignant Mixed Neoplasm

Malignant Mixed Tumor

Mixed Neoplasm

Mixed Tumor, Malignant

Malignant Mixed Cancer

Mixed Tumor

Malignant Mixed Tumor, Not Otherwise Specified

Mixed Salivary Gland Tumor

Mixed Tumor, Not Otherwise Specified

Clear Cell Meningioma

Anal Paget'S Disease

Anal Paget Disease

Paget'S Disease Of Anus

Paget'S Disease Of The Anus

Paget Disease Of The Anus

Breast Ductal Carcinoma

Ductal Breast Carcinoma

Duct Carcinoma

Carcinoma, Ductal

Mammary Ductal Carcinoma

Ductal Carcinoma

Inner Ear Disease

Labyrinthine Dysfunction

Diseases Of Inner Ear

Labyrinthine Disease

Abnormality Of The Inner Ear

Labyrinth Diseases

Labyrinthine Disorder

Nonfunctioning Labyrinth

Labyrinthine Loss Of Function

Labyrinthine Syndrome

Labyrinthine Disorder Nos

Intracranial Primitive Neuroectodermal Tumor

Intracranial Pnet

Intracranial Primitive Neuroectodermal Neoplasm

Retinoblastoma

RB

Trilateral Retinoblastoma

RB1

Retinoblastoma, Trilateral

Neuroblastoma Of Retina

Rb - Retinoblastoma

Eye Cancer, Retinoblastoma

Retinal Cancer

Retinal Tumor

Glioma, Retinal

Non-Hereditary Retinoblastoma

Childhood Cancer Retinoblastoma

Malignant Neoplasm Of Retina

Retinal Neoplasms

Insulinoma

Islet Cell Adenoma

Insulin-Producing Tumor Of Islet Cells

Adenoma Islet Cell

Islet Cell Tumor

Experimental Organism Islet Cell Adenoma Neoplasm

Chondrosarcoma, Extraskeletal Myxoid

Extraskeletal Myxoid Chondrosarcoma

Emc

Myxoid Extraosseous Chondrosarcoma

Ovarian Germ Cell Cancer

Ovarian Germ Cell Tumor

Malignant Germ Cell Tumor Of Ovary

Germ Cell Neoplasm Of Ovary

Germ Cell Tumor Of Ovary

Mogct

Malignant Ovarian Germ Cell Tumor

Malignant Ovarian Germ Cell Neoplasm

Lymphoepithelioma-Like Carcinoma

Lymphoepithelial Carcinoma

Nasopharyngeal Type Undifferentiated Carcinoma

Keratinizing Squamous Cell Carcinoma

Squamous Cell Carcinoma, Keratinizing

Keratinizing Epidermoid Carcinoma

Pancreatic Gastrinoma

Pancreatic G-Cell Tumor

Appendix Adenocarcinoma

Cystadenocarcinoma

Mucinous Adenocarcinoma

Adenocarcinoma Of Appendix

Appendiceal Adenocarcinoma

Adenocarcinoma Of The Appendix

Colonic Type Adenocarcinoma

Nonmucinous Adenocarcinoma

Mature Teratoma Of The Ovary

Ovarian Small Cell Carcinoma

Small Cell Carcinoma Of The Ovary

Scco

Small Cell Ovarian Carcinoma

Cerebellar Hypoplasia

Pancreatic Endocrine Carcinoma

Carcinoma Of Endocrine Pancreas

Islet Cell Carcinoma

Malignant Neoplasm Of Islets Of Langerhans

Pancreatic Neuroendocrine Carcinoma

Carcinoma Islet Cell

Carcinoma, Islet Cell

Mature Teratoma

Dermoid Cyst

Benign Teratoma

Thyroid Gland Cancer

Thyroid Gland Carcinoma

Malignant Neoplasm Of Thyroid Gland

Malignant Tumour Of Thyroid Gland

Thyroid Neoplasm

Thyroid Neoplasms

Neoplasm Of Thyroid Gland

Thyroid Gland Neoplasm

Head And Neck Cancer, Thyroid

Neoplasm Of The Thyroid Gland

Cancer Of The Thyroid

Primary Malignant Neoplasm Of Thyroglossal Duct

Malignant Neoplasm Of Thyroglossal Duct

Primary Malignant Neoplasm Of Thyroid Gland

Thyroglossal Duct Cancer

Toxic Goitre Malignant Tumour

Cancerous Goitre

Attention Deficit-Hyperactivity Disorder

Attention Deficit Hyperactivity Disorder

ADHD

Attention Deficit Disorder

Attention Deficit-Hyperactivity Disorder, Susceptibility To

Attention Deficit Disorder With Hyperactivity

Hyperkinetic Disorder

Hyperactivity Of Childhood

Attention-Deficit/Hyperactivity Disorder

Add

Addh

Attention Deficit

Attention Deficit Disorder Of Childhood With Hyperactivity

Attention Deficit Disorder With Hyperactivity Syndrome

Hyperkinetic Syndrome

Attention-Deficit Hyperactivity Disorder

Attention-Deficit/Hyperactivity Disorder, Predominantly Inattentive Type

Disturbance Of Activity And Attention

Disorder Of Activity And Attention

Adhd - [Attention Deficit Hyperactivity Disorder]

Hyperkinetic Disorders

Disorder Of Activity And Attention With Hyperkinesia

Attention Deficit Syndrome With Hyperactivity

Vulvar Eccrine Porocarcinoma

Desmoplastic Small Round Cell Tumor

Dsrct

Desmoplastic Small Round-Cell Tumor

Desmoplastic Small Round-Cell Neoplasm

Thymus Basaloid Carcinoma

Basaloid Carcinoma Of The Thymus

Thymic Basaloid Carcinoma

Cecal Disease

Cecal Diseases

Disorder Of Cecum

Desmoplastic Nodular Medulloblastoma

Medulloblastoma With Extensive Nodularity

Nodular Medulloblastoma

Desmoplastic/Nodular Medulloblastoma

Mben

Medulloblastoma, With Extensive Nodularity

Alzheimer Disease, Familial, 1

Alzheimer Disease

Alzheimer'S Disease

Presenile And Senile Dementia

AD1

Alzheimer Disease, Susceptibility To

Alzheimer Disease, Late-Onset, Susceptibility To

Alzheimer Disease 1, Familial

AD

Familial Alzheimer Disease

Alzheimer Disease, Late-Onset

Alzheimers Dementia

Alzheimer Dementia

Alzheimer Sclerosis

Alzheimer Syndrome

Alzheimer-Type Dementia

Dat

Primary Senile Degenerative Dementia

Sdat

Alzheimer Disease 1

Autosomal Dominant Alzheimer Disease

Early-Onset Alzheimer Disease With Cerebral Amyloid Angiopathy

Late Onset Alzheimer Disease

Alzheimers Disease

Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy

Late-Onset Alzheimers Disease

Alzheimer'S Disease Pathway Kegg

Dementia Due To Alzheimer'S Disease

Alzheimer Disease Type 1

Alzheimers

Frontotemporal Dementia

Pallidopontonigral Degeneration

Frontotemporal Lobar Degeneration

Semantic Dementia

FTD

Frontotemporal Lobe Dementia

Multiple System Tauopathy With Presenile Dementia

Dementia, Frontotemporal

Frontotemporal Dementia With Parkinsonism

Mstd

Frontotemporal Lobar Degeneration With Tau Inclusions

Ftld With Tau Inclusions

Dementia, Frontotemporal, With Parkinsonism

Fldem

Ftdp17

Disinhibition-Dementia-Parkinsonism-Amyotrophy Complex

Ddpac

Wilhelmsen-Lynch Disease

Wld

Ppnd

Dementia, Frontotemporal, With Or Without Parkinsonism

Semantic Primary Progressive Aphasia

Semantic Variant Ppa

Wilhemsen-Lynch Disease

Frontotemporal Dementia-Amyotrophic Lateral Sclerosis

Frontotemporal Dementia And Parkinsonism Linked To Chromosome 17

Ftd-Als

Ftld

Pick Complex

Pick Disease Of The Brain

Frontotemporal Dementia With Parkinsonism-17

Grn-Related Frontotemporal Dementia

Frontotemporal Dementia With Motor Neuron Disease

Dementia In Fronto-Temporal Lobar Degeneration

Ftd - [Frontotemporal Dementia]

Temple Dementia

Frontal Lobe Dementia

Acinar Cell Carcinoma

Acinic Cell Carcinoma

Acinic Cell Tumor

Carcinoma Acinar Cell

Carcinoma, Acinar Cell

Acinar Cell Tumor

Esophageal Atresia

Tracheoesophageal Fistula

Congenital Atresia Of Esophagus

Congenital Imperforate Esophagus

Imperforate Esophagus

Oesophageal Atresia

Te Fistula

Tef

Tracheoesophageal Fistula With Or Without Esophageal Atresia

Ectopic Cushing Syndrome

Cushing Syndrome Due To Ectopic Acth Secretion

Ectopic Acth Secreting Tumor

Adrenocorticotropic Hormone Secretion Syndrome

Occult Ectopic Acth Secretion

Paraneoplastic Cushing Syndrome

Basal Cell Carcinoma

Basal Cell Cancer

Basal Cell Neoplasm

Basal Cell Carcinoma Of Skin

Malignant Basal Cell Tumor

Basal Cell Tumor

Epithelioma Basal Cell

Malignant Basal Cell Neoplasm

Rodent Ulcer

Carcinoma Basal Cell

Neoplasms, Basal Cell

Basal Cell Carcinomas

Experimental Organism Basal Cell Carcinoma

Nodulo-Ulcerative Basal Cell Carcinoma

Basalioma

Basal Cell Epithelioma Of Skin

Bcc - [Basal Cell Carcinoma] Of Skin

Rodent Ulcer Of Skin

Rodent Ulcer Of Unspecified Site

Basal Cell Epithelioma Of Unspecified Site

Cranial Nerve Palsy

Cranial Nerve Paralysis

Cranial Nerve Diseases

Cranial Nerve Palsies

Prostatic Acinar Adenocarcinoma

Acinar Prostate Adenocarcinoma

Chordoid Glioma

Chordoid Glioma Of The Third Ventricle

Central Nervous System Benign Neoplasm

Benign Neoplasm Of The Central Nervous System

Prostate Small Cell Carcinoma

Small Cell Carcinoma Of Prostate

Prostate Oat Cell Carcinoma

Struma Ovarii

Duodenal Gastrinoma

Duodenal G-Cell Gastrin Producing Tumor

Gastrinoma Of Duodenum

Malignant Duodenal Gastrinoma

Duodenal Gastrin-Producing Neuroendocrine Tumor

Meibomian Cyst

Chalazion

Meibomian Gland Lipogranuloma

Tarsal Cyst

Rectum Squamous Cell Carcinoma

Squamous Cell Carcinoma Of The Rectum

Rectal Squamous Cell Carcinoma

Squamous Carcinoma Of Rectum

Endocrine Organ Benign Neoplasm

Prostate Stromal Sarcoma

Stromal Sarcoma Of The Prostate

Subleukemic Leukemia

Aleukemic Leukemia Cutis

Leukemia Subleukemic

Adenosquamous Prostate Carcinoma

Adenosquamous Carcinoma Of Prostate

Adenosquamous Carcinoma Of The Prostate

Rhabdomyosarcoma

Lung Combined Large Cell Neuroendocrine Carcinoma

Combined Large Cell Neuroendocrine Carcinoma Of Lung

Pulmonary Combined Large Cell Neuroendocrine Carcinoma

Combined Large Cell Lung Neuroendocrine Carcinoma

Lumbosacral Plexus Lesion

Lumbosacral Plexus Lesions

Pleomorphic Xanthoastrocytoma

Pxa

Pleomorphic Xantho-Astrocytoma

Cauda Equina Syndrome

Cauda Equina

Polyradiculopathy

Skin Carcinoma

Skin Cancer

Carcinoma Of Skin

Ca - Skin Cancer

Cancer Of Skin

Malignant Neoplasm Of Skin

Melanoma And Non-Melanoma Skin Cancer

Skin Cancers

Cancer, Skin

Mucinous Cystadenofibroma

Endometrial Transitional Cell Carcinoma

Pancreas Lymphoma

Lymphoma Of Pancreas

Bilateral Hypoactive Labyrinth

Hypoactive Bilateral Labyrinthine Dysfunction

Hypoactive Labyrinth, Bilateral

Tracheal Cancer

Tracheal Carcinoma

Malignant Neoplasm Of Trachea

Tracheal Neoplasms

Pancoast Tumor

Pulmonary Sulcus Neoplasm

Pancoast Syndrome

Small Cell Osteogenic Sarcoma

Small Cell Osteosarcoma

Round Cell Osteosarcoma

Osteosarcoma Small Cell

Cystitis Cystica

Extracranial Neuroblastoma

Neural Tube Defects

Spina Bifida

Neural Tube Defect

NTD

Neural Tube Defects, Susceptibility To

Spinal Dysraphism

Spina Bifida, Susceptibility To

Rachischisis

Cleft Spine

Open Spine

Hydrocele Spinalis

Neural Tube Defect Nos

Sb - [Spina Bifida]

Spinal Hernia Nos

Spinal Fissure Nos

Orbital Cancer

Malignant Neoplasm Of Orbit

Orbital Tumor

Orbital Neoplasms

Neoplasm Of Orbit Proper

Orbit Cancer

Primary Malignant Neoplasm Of Orbit

Intraorbital Cancer

Glycogen-Rich Clear Cell Breast Carcinoma

Glycogen-Rich Carcinoma

Cerebellar Medulloblastoma

Papillary Adenoma

Glandular Papilloma

Adenoma

Rectum Neuroendocrine Neoplasm

Neuroendocrine Tumor Of Rectum

Neuroendocrine Tumor Of The Rectum

Net Of The Rectum

Rectal Net

Rectal Neuroendocrine Tumor

Rectal Neuroendocrine Neoplasm

Cerebellopontine Angle Primitive Neuroectodermal Tumor

Cerebellopontine Angle Pnet

Gastric Gastrinoma

Gastric G-Cell Gastrin Producing Tumor

Gastric Gastrin-Producing Neuroendocrine Tumor

Large Cell Medulloblastoma

Pancreatic Cystadenoma

Cystadenoma Of Pancreas

Respiratory System Benign Neoplasm

Gallbladder Adenocarcinoma

Adenocarcinoma Of The Gallbladder

Carcinoma Of The Gallbladder

Vascular Cancer

Blood Vessel Tumors

Malignant Vascular Neoplasm

Renal Vein Leiomyosarcoma

Vascular Neoplasms

Blood Vessel Neoplasm

Blood Vessel Tumor

Blood Vessel Tumour Disorder

Haemangiomatous Tumour

Leiomyosarcoma Of The Renal Vein

Malignant Great Vessel Tumor

Malignant Tumor Of Pulmonary Artery

Malignant Tumor Of Pulmonary Vein

Malignant Vascular Tumor

Neoplasm Of Great Vessel

Pulmonary Artery Malignant Neoplasm

Pulmonary Vein Malignant Neoplasm

Vascular Tissue Neoplasm

Vascular Tumors

Blood Vessel Cancer

Neoplasms, Vascular Tissue

Malignant Neoplasm Of Great Vessels

Anaplastic Ependymoma

Ependymoma, Anaplastic

Undifferentiated Ependymoma

Neurohypophysis Granular Cell Tumor

Granular Cell Tumor Of The Neurohypophysis

Optic Nerve Astrocytoma

Astrocytic Tumor Of Optic Nerve

Optic Tract Astrocytoma

Visual Pathway Astrocytoma

Ovarian Cystic Teratoma

Papilledema

Choked Disk

Edema Of The Optic Disc

Myoblastoma

Benign Granular Cell Tumor

Vaginal Tubulovillous Adenoma

Pineal Region Teratoma

Teratoma Of Pineal Area

Horner'S Syndrome

Horner Syndrome

Bernard-Horner Syndrome

Oculosympathetic Palsy

Bernard Horner Syndrome

Cervical Sympathetic Paralysis

Von Passow Syndrome

Cervical Sympathetic Dystrophy

Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor

Extraosseous Ewing'S Tumor

Extraosseous Ewing'S Tumour

Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumour

Benign Ileal Neoplasm

Ileal Tumor

Ileal Neoplasms

Ileal Neoplasm

Thyroid Gland Medullary Carcinoma

Medullary Thyroid Carcinoma

Medullary Carcinoma Of The Thyroid Gland

Ultimobranchial Thyroid Tumor

Ultimobranchial Thyroid Tumour

Thyroid Cancer, Medullary

Amelanotic Melanoma

Melanoma, Amelanotic

Melanoma Amelanotic

Amelanotic Skin Melanoma

Cutaneous Ganglioneuroma

Ganglioneuroma Of Skin

Subungual Glomus Tumor

Subungual Glomus Tumour

Myxopapillary Ependymoma

Ependymoma Myxopapillary

Salpingitis Isthmica Nodosa

Adrenal Gland Disease

Adrenal Gland Diseases

Adrenal Gland Disorders

Papillary Thymic Adenocarcinoma

Papillary Carcinoma Of The Thymus

Amyotrophic Lateral Sclerosis 1

Amyotrophic Lateral Sclerosis

ALS

Lou Gehrig Disease

Amyotrophic Lateral Sclerosis Type 1

Charcot Disease

ALS1

Amyotrophic Lateral Sclerosis, Susceptibility To

Fals

Lou Gehrig'S Disease

Mnd

Motor Neuron Disease

Familial Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis 1, Familial

Amyotrophic Lateral Sclerosis 1, Autosomal Dominant

Motor Neuron Disease, Bulbar

Motor Neurone Disease

Amyotrophic Lateral Sclerosis With Dementia

Dementia With Amyotrophic Lateral Sclerosis

Motor Neuron Disease, Amyotrophic Lateral Sclerosis

Sclerosis, Lateral, Amyotrophic

Sclerosis, Lateral, Amyotrophic, Type 1

Amyotrophic Sclerosis

Als - [Amyotrophic Lateral Sclerosis]

Wasting Palsy

Amyotrophic Paralysis

Amyotrophy Lateral Sclerosis

Wasting Paralysis

Spinal Progressive Amyotrophy

Progressive Atrophic Paralysis

Bile Duct Mucinous Adenocarcinoma

Mucinous Carcinoma Of The Bile Duct

Extrahepatic Bile Duct Mucinous Adenocarcinoma

Differentiating Neuroblastoma

Cardiovascular Organ Benign Neoplasm

Neuroblastoma

Nb

Neuroblastoma, Susceptibility To

Neuroblastomas

Central Neuroblastoma

Pineal Region Choriocarcinoma

Pineal Choriocarcinoma

Skeletal Muscle Cancer

Malignant Tumor Of Skeletal Muscle

Skeletal Muscle Neoplasm

Obstructive Jaundice

Jaundice, Obstructive

Cholestatic Jaundice

Cholestatic Jaundice Syndrome

Obstructive Hyperbilirubinemia

Jaundice Obstructive

Jaundice Cholestatic

Orbital Disease

Orbit

Orbital Diseases

Endobronchial Lipoma

Exophthalmos

Proptosis

Vulva Basal Cell Carcinoma

Basal Cell Carcinoma Of Vulva

Basal Cell Carcinoma Of The Vulva

Neurilemmoma

Schwannoma

Benign Schwannoma

Neurilemoma

Peripheral Fibroblastoma

Psammomatous Schwannoma

Neurolemmoma

Schwannomas

Adrenal Cortex Disease

Adrenal Cortex Diseases

Muscle Cancer

Myosarcoma

Malignant Neoplasm Of Muscle

Malignant Tumor Of Muscle

Malignant Tumor Of The Muscle

Muscle Neoplasms

Myomatous Neoplasm

Pineal Region Meningioma

Pineal Meningioma

Hyperinsulinemic Hypoglycemia

Nesidioblastosis

Islet Cell Hyperplasia

Persistent Hyperinsulinemia Hypoglycemia Of Infancy

Hyperinsulinemic Hypoglycaemia

Suppression Of Tumorigenicity 12

Prostate Adenocarcinoma

Adenocarcinoma Of Prostate

ST12

Prostate Adenocarcinoma 1

Pac1

Low Grade Glioma

Benign Glioma

Parathyroid Adenoma

Adenoma Of Parathyroid

Adenoma Of The Parathyroid Gland

Parathyroid Gland Adenoma

Frontal Lobe Neoplasm

Neoplasm Of Frontal Lobe

Malignant Neoplasm Of Frontal Lobe

Tumor Of Frontal Lobe

Thymus Sarcomatoid Carcinoma

Thymic Carcinosarcoma

Thymic Sarcomatoid Carcinoma

Multiple Endocrine Neoplasia, Type I

Multiple Endocrine Neoplasia Type 1

MEN1

Wermer Syndrome

Multiple Endocrine Neoplasia 1

Multiple Endocrine Neoplasia, Type 1

Men I

Endocrine Adenomatosis, Multiple

Mea I

Men Type I

Wermer'S Syndrome

Men1 Syndrome

Multiple Endocrine Adenomatosis

Endocrine Adenomatosis Multiple

Men 1

Familial Multiple Endocrine Neoplasia Type I

Neoplasia, Endocrine, Multiple, Type 1

Multiple Endocrine Neoplasia

Lipoma Of Spermatic Cord

Spermatic Cord Lipoma

Paratesticular Lipoma

Bipolar Disorder

Bipolar Depression

Manic Disorder

Depression, Bipolar

Bipolar Disorder Manic Phase

Depressive-Manic Psych.

Manic Bipolar Affective Disorder

Manic Bipolar I Disorder

Manic Depression

Manic Depressive Disorder

Mixed Bipolar Disorder

Bipolar Affective Disorder

Bipolar Affective Psychosis

Bipolar Spectrum Disorder

Manic Depressive Illness

Depression Bipolar

Bipolar Disorder, Mixed

Major Affective Disorder

Major Affective Disorder 1

Major Affective Disorder 2

Nasal Cavity Olfactory Neuroblastoma

Olfactory Neuroblastoma Of The Nasal Cavity

Spinal Cord Disease

Spinal Cord Diseases

Myelopathy

Bone Marrow Diseases

Peripheral Nervous System Neoplasm

Peripheral Nervous System Neoplasms

Nerve Sheath Neoplasm

Neoplasm Of Peripheral Nerve

Tumor Of Pns

Nerve Sheath Neoplasms

Nerve Sheath Tumors

Von Hippel-Lindau Syndrome

Von Hippel-Lindau Disease

Vhl

Vhl Syndrome

VHLS

Von Hippel-Lindau Syndrome, Modifier Of

Hippel Lindau Syndrome

Angiomatosis Retinae

Cerebelloretinal Angiomatosis, Familial

Hippel-Lindau Disease

Familial Cerebelloretinal Angiomatosis

Lindau Disease

VHLD

Ovary Leiomyosarcoma

Leiomyosarcoma Of Ovary

Breast Cancer

Breast Carcinoma

Male Breast Cancer

Breast Cancer, Familial

Malignant Neoplasm Of Breast

Breast Cancer, Susceptibility To

Breast Cancer, Early-Onset

Malignant Tumor Of Breast

Carcinoma Of Male Breast

Breast Cancer, Invasive Ductal

Breast Cancer, Protection Against

Breast Cancer, Somatic

Breast Cancer, Male

Breast Cancer, Lobular, Somatic

Breast Tumor

Mammary Cancer

Mammary Tumor

Malignant Neoplasm Of Male Breast

Mammary Carcinoma

Male Breast Carcinoma

Familial Cancer Of Breast

Invasive Ductal Breast Carcinoma

Breast Cancer Susceptibility

Breast Cancer, Male, Susceptibility To

Breast Cancer, Early-Onset, Susceptibility To

Malignant Tumor Of The Breast

Mammary Neoplasm

Primary Breast Cancer

Neoplasm Of Male Breast

Carcinoma Of Breast

Breast Cancer In Men

Familial Breast Cancer

Cancer Of Breast

BC

Breast Cancer Familial

Breast Cancer Familial Male

Breast Cancer, Familial Male

Breast Male Carcinoma

Breast Neoplasms

Breast Neoplasms, Male

Mammary Tumors

Mammary Carcinomas

Cancer, Breast

Cancer, Breast, Susceptibility

Invasive Breast Ductal Carcinoma

Breast Neoplasm

Susceptibility To Breast Cancer

Mammary Neoplasms

Animal Mammary Neoplasms

Primary Malignant Neoplasm Of Breast

Infiltrating Ductal Carcinoma Of Breast

Infiltrating Duct Carcinoma Of Unspecified Site

Infiltrating Ductular Carcinoma Of Unspecified Site

Invasive Breast Carcinoma Of No Special Type

Microinvasive Carcinoma Of Breast

Carcinoma With Apocrine Differentiation

Infratentorial Cancer

Infratentorial Neoplasms

Brain Neoplasm, Infratentorial

Malignant Infratentorial Tumors

Mediastinal Lipomatosis

Pancreatic Cancer

Pancreatic Carcinoma

Carcinoma Of Pancreas

Familial Pancreatic Carcinoma

Pancreatic Neoplasm

Pancreatic Carcinoma, Familial

Malignant Neoplasm Of Pancreas

Pancreatic Acinar Carcinoma

Pancreatic Tumor

Familial Pancreatic Cancer

Neoplasm Of The Pancreas

Cancer Of The Pancreas

Pancreatic Carcinoma, Somatic

Pancreatic Cancer, Somatic

Ca Body Of Pancreas

Ca Head Of Pancreas

Ca Tail Of Pancreas

Malignant Neoplasm Of Body Of Pancreas

Malignant Neoplasm Of Head Of Pancreas

Malignant Neoplasm Of Tail Of Pancreas

Pancreas Neoplasm

Exocrine Cancer

Exocrine Pancreas Carcinoma

Hereditary Pancreatic Cancer

Hereditary Pancreatic Carcinoma

PNCA

Pancreatic Cancer, Susceptibility To

Carcinoma Of Head Of Pancreas

Pancreatic Neoplasms

Pancreatic Tumors

Cancer, Pancreatic

Cancer Of Pancreas

Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site

Aceruloplasminemia

Cerebellar Ataxia

Hypoceruloplasminemia

Hemosiderosis, Systemic, Due To Aceruloplasminemia

Familial Apoceruloplasmin Deficiency

Hereditary Ceruloplasmin Deficiency

Deficiency Of Ferroxidase

Hypoceruloplasminemia, Hereditary

Ceruloplasmin Deficiency

Systemic Hemosiderosis Due To Aceruloplasminemia

ACERULOP

Anus Basaloid Carcinoma

Basaloid Carcinoma Of The Anus

Anal Basaloid Carcinoma

Gastrointestinal System Benign Neoplasm

Toxic Encephalopathy

Neurotoxicity

Neurotoxicity Syndromes

Neurotoxicity Syndrome

Encephalopathy, Toxic

Cerebral Degeneration

Brain Degeneration

Degenerative Brain Disorder

Vaginal Adenoma

Cell Type Benign Neoplasm

Giant Cell Glioblastoma

Monstrocellular Sarcoma

Pilomyxoid Astrocytoma

Dementia, Lewy Body

Lewy Body Dementia

Lewy Body Disease

Diffuse Lewy Body Disease

Dementia With Lewy Bodies

DLB

Autosomal Dominant Diffuse Lewy Body Disease

Cortical Lewy Body Disease

Dementia, Lewy Body, Susceptibility To

Lewy Body Dementia, Susceptibility To

Senile Dementia Of The Lewy Body Type

Dementia Of The Lewy Body Type

Lbd

Diffuse Lewy Body Disease With Gaze Palsy

Dysphasic Dementia Hereditary

Lewy Body Type Senile Dementia

Lewy Body Variant Of Alzheimer Disease

Lewy Bodies

Lewy Body

Dlbd - [Diffuse Lewy Body Disease]

Clbd - [Cortical Lewy Body Disease]

Bone Osteosarcoma

Osteosarcoma Of Bone

Primary Osteosarcoma Of Bone

Thyroid Gland Hurthle Cell Carcinoma

Oncocytic Carcinoma Of The Thyroid

Thyroid Cancer, Hurthle Cell

Autonomic Nervous System Neoplasm

Tumor Of Autonomic Nervous System

Schizophrenia

SCZD

Schizophrenia With Or Without An Affective Disorder

Schizophrenia 12

Schizophrenia, Susceptibility To

Schizophrenia-1

Dementia Praecox

Schizophrenia 1

Rhabdomyosarcoma 2

Alveolar Rhabdomyosarcoma

Rhabdomyosarcoma, Alveolar

Rhabdomyosarcoma Alveolar

RMS2

Rmsa

Rhabdomyosarcoma 2, Alveolar

Alveolar Childhood Rhabdomyosarcoma

Arms

Rhabdomyosarcoma, Type 2

Thymus Large Cell Carcinoma

Large Cell Carcinoma Of The Thymus

Thymic Large Cell Neuroendocrine Carcinoma

Cystic Basal Cell Carcinoma

Skin Cystic Basal Cell Carcinoma

Pick Disease Of Brain

Pick Disease

Pick'S Disease

Pick Disease Of The Brain

Lobar Atrophy Of Brain

Dementia With Lobar Atrophy And Neuronal Cytoplasmic Inclusions

Behavioral Variant Of Frontotemporal Dementia

Dementia In Pick'S Disease

Lobar Atrophy Of The Brain

Bvftd

Bv-Ftd

PIDB

Picks Disease

Vaginal Benign Neoplasm

Prostate Signet Ring Cell Adenocarcinoma

Prostate Signet Ring Cell Carcinoma

Signet Ring Cell Carcinoma Of Prostate

Acinar Prostate Adenocarcinoma, Signet Ring Variant

Vulvar Proximal-Type Epithelioid Sarcoma

Central Epithelioid Sarcoma

Proximal-Type Epithelioid Sarcoma

Ewing Sarcoma

Neuroepithelioma

Ewing'S Tumor

Primitive Neuroectodermal Tumor

Ewings Sarcoma

Ewing'S Sarcoma

Peripheral Neuroepithelioma

ES

Ewings Sarcoma-Primitive Neuroectodermal Tumor

Localized Peripheral Primitive Neuroectodermal Tumor

Peripheral Primitive Neuroectodermal Tumor

Ewing Tumor

Sarcoma, Ewing'S

Ewing Family Of Tumors

Extraosseous Ewing Tumor

Askin Tumor

Ewing'S Family Localized Tumor

Ewing'S Sarcoma/Peripheral Primitive Neuroectodermal Tumor

Localized Ewing Sarcoma

Localized Ewing'S Sarcoma

Localized Ewing'S Sarcoma/Peripheral Primitive Neuroectodermal Tumor

Localized Ewing'S Tumor

Pnet Of Thoracopulmonary Region

Tumor Of The Ewing Family

Skeletal Ewing Sarcoma

Osseous Ewing Sarcoma

Ppnet

Peripheral Pnet

Extraskeletal Ewing Sarcoma

Eoe

Extraosseous Ewing Sarcoma

Extraskeletal Ewing Tumor

Esft

Ewing Sarcoma Family Of Tumors

Pne

Pnet

Pnet Of The Chest Wall

Sarcoma, Ewing

Neuroectodermal Tumors, Primitive, Peripheral

Neuroectodermal Tumor, Primitive

Disorder Of Eye

Askin'S Tumor

Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor

Neuroepithelioma, Peripheral

Peripheral Nervous System Disease

Peripheral Neuropathy

Peripheral Nerve Disease

Peripheral Nerve Disorders

Neuropathy, Peripheral

Peripheral Neuropathy Due To Vitamin Pyridoxine Hyperalimentation

Gliosarcoma

Glioblastoma With Sarcomatous Component

Sarcomatous Glioblastoma

Wilms Tumor 1

Nephroblastoma

Wilms Tumor

WT1

Wilms' Tumor

Bilateral Wilms Tumor

Wilms Tumor, Type 1

Wilms Tumor, Somatic

Adult Nephroblastoma

Wt1 Disorder

Renal Embryonic Tumor

Adult Kidney Wilms Tumor

Childhood Kidney Wilms Tumor

Nonanaplastic Kidney Wilms Tumor

Nervous System Disease

Abnormality Of The Nervous System

Nervous System Diseases

Nervous System Disorder

Retinitis Pigmentosa

RP

Rod-Cone Dystrophy

Autosomal Recessive Retinitis Pigmentosa

Non-Syndromic Retinitis Pigmentosa

Pericentral Pigmentary Retinopathy

Pigmentary Retinopathy

Tapetoretinal Degeneration

Rcd

Retinitis Pigmentosa Autosomal Recessive

ARRP

Retinitis Pigmentosa, Autosomal Recessive

Retinitis Pigmentosa 1

疾病名称

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Synaptophysin Antibody

Synaptophysin Antibody #4329

Citations (43)

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Western blot analysis of extracts from rat brain, mouse brain and human cerebellum using Synaptophysin Antibody.

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Western blot analysis of extracts from rat brain, mouse brain and human cerebellum using Synaptophysin Antibody.

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Supporting Data

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Supporting Data

REACTIVITY

H M R

SENSITIVITY

Endogenous

MW (kDa)

38

SOURCE

Rabbit

Application Key:

WB-Western Blot

IP-Immunoprecipitation

IHC-Immunohistochemistry

ChIP-Chromatin Immunoprecipitation

C&R-CUT&RUN

C&T-CUT&Tag

DB-Dot Blot

eCLIP-eCLIP

IF-Immunofluorescence

F-Flow Cytometry

Species Cross-Reactivity Key:

H-Human

M-Mouse

R-Rat

Hm-Hamster

Mk-Monkey

Vir-Virus

Mi-Mink

C-Chicken

Dm-D. melanogaster

X-Xenopus

Z-Zebrafish

B-Bovine

Dg-Dog

Pg-Pig

Sc-S. cerevisiae

Ce-C. elegans

Hr-Horse

GP-Guinea Pig

Rab-Rabbit

All-All Species Expected

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Product Information

Product Usage Information

Application

Dilution

Western Blotting

1:1000

Storage

Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.

Protocol

Select your Protocol

Western Blotting

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Western Blotting Protocol

For western blots, incubate membrane with diluted primary antibody in 5% w/v BSA, 1X TBS, 0.1% Tween® 20 at 4°C with gentle shaking, overnight.

NOTE: Please refer to primary antibody product webpage for recommended antibody dilution.

A. Solutions and Reagents

From sample preparation to detection, the reagents you need for your Western Blot are now in one convenient kit: #12957 Western Blotting Application Solutions Kit

NOTE: Prepare solutions with reverse osmosis deionized (RODI) or equivalent grade water.

20X Phosphate Buffered Saline (PBS): (#9808) To prepare 1 L 1X PBS: add 50 ml 20X PBS to 950 ml dH2O, mix.

10X Tris Buffered Saline (TBS): (#12498) To prepare 1 L 1X TBS: add 100 ml 10X to 900 ml dH2O, mix.

1X SDS Sample Buffer: Blue Loading Pack (#7722) or Red Loading Pack (#7723) Prepare fresh 3X reducing loading buffer by adding 1/10 volume 30X DTT to 1 volume of 3X SDS loading buffer. Dilute to 1X with dH2O.

10X Tris-Glycine SDS Running Buffer: (#4050) To prepare 1 L 1X running buffer: add 100 ml 10X running buffer to 900 ml dH2O, mix.

10X Tris-Glycine Transfer Buffer: (#12539) To prepare 1 L 1X Transfer Buffer: add 100 ml 10X Transfer Buffer to 200 ml methanol + 700 ml dH2O, mix.

10X Tris Buffered Saline with Tween® 20 (TBST): (#9997) To prepare 1 L 1X TBST: add 100 ml 10X TBST to 900 ml dH2O, mix.

Nonfat Dry Milk: (#9999).

Blocking Buffer: 1X TBST with 5% w/v nonfat dry milk; for 150 ml, add 7.5 g nonfat dry milk to 150 ml 1X TBST and mix well.

Wash Buffer: (#9997) 1X TBST.

Bovine Serum Albumin (BSA): (#9998).

Primary Antibody Dilution Buffer: 1X TBST with 5% BSA; for 20 ml, add 1.0 g BSA to 20 ml 1X TBST and mix well.

Biotinylated Protein Ladder Detection Pack: (#7727).

Blue Prestained Protein Marker, Broad Range (11-250 kDa): (#59329).

Blotting Membrane and Paper: (#12369) This protocol has been optimized for nitrocellulose membranes. Pore size 0.2 µm is generally recommended.

Secondary Antibody Conjugated to HRP: Anti-rabbit IgG, HRP-linked Antibody (#7074).

Detection Reagent: SignalFire™ ECL Reagent (#6883).

B. Protein Blotting

A general protocol for sample preparation.

Treat cells by adding fresh media containing regulator for desired time.

Aspirate media from cultures; wash cells with 1X PBS; aspirate.

Lyse cells by adding 1X SDS sample buffer (100 µl per well of 6-well plate or 500 µl for a 10 cm diameter plate). Immediately scrape the cells off the plate and transfer the extract to a microcentrifuge tube. Keep on ice.

Sonicate for 10–15 sec to complete cell lysis and shear DNA (to reduce sample viscosity).

Heat a 20 µl sample to 95–100°C for 5 min; cool on ice.

Microcentrifuge for 5 min.

Load 20 µl onto SDS-PAGE gel (10 cm x 10 cm).

NOTE: Loading of prestained molecular weight markers (#59329, 10 µl/lane) to verify electrotransfer and biotinylated protein ladder (#7727, 10 µl/lane) to determine molecular weights are recommended.

Electrotransfer to nitrocellulose membrane (#12369).

C. Membrane Blocking and Antibody Incubations

NOTE: Volumes are for 10 cm x 10 cm (100 cm2) of membrane; for different sized membranes, adjust volumes accordingly.

I. Membrane Blocking

(Optional) After transfer, wash nitrocellulose membrane with 25 ml TBS for 5 min at room temperature.

Incubate membrane in 25 ml of blocking buffer for 1 hr at room temperature.

Wash three times for 5 min each with 15 ml of TBST.

II. Primary Antibody Incubation

Incubate membrane and primary antibody (at the appropriate dilution and diluent as recommended in the product webpage) in 10 ml primary antibody dilution buffer with gentle agitation overnight at 4°C.

Wash three times for 5 min each with 15 ml of TBST.

Incubate membrane with Anti-rabbit IgG, HRP-linked Antibody (#7074 at 1:2000) and anti-biotin, HRP-linked Antibody (#7075 at 1:1000–1:3000) to detect biotinylated protein markers in 10 ml of blocking buffer with gentle agitation for 1 hr at room temperature.

Wash three times for 5 min each with 15 ml of TBST.

Proceed with detection (Section D).

D. Detection of Proteins

Directions for Use:

Wash membrane-bound HRP (antibody conjugate) three times for 5 minutes in TBST.

Prepare 1X SignalFire™ ECL Reagent (#6883) by diluting one part 2X Reagent A and one part 2X Reagent B (e.g. for 10 ml, add 5 ml Reagent A and 5 ml Reagent B). Mix well.

Incubate substrate with membrane for 1 minute, remove excess solution (membrane remains wet), wrap in plastic and expose to X-ray film.

* Avoid repeated exposure to skin.

posted June 2005

revised June 2020

Protocol Id: 10

Specificity / Sensitivity

Synaptophysin Antibody detects endogenous levels of total synaptophysin protein.

Species Reactivity:

Human, Mouse, Rat

Source / Purification

Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ala230 of human synaptophysin. Antibodies are purified by peptide affinity chromatography.

Background

Synaptophysin (SYP) is a neuronal synaptic vesicle glycoprotein that is expressed in neuroendocrine cells and neoplasms (1). Synaptophysin contains four transmembrane domains that form a hexameric channel or gap junction-like pore (2). Synaptophysin binds to the SNARE protein synaptobrevin/VAMP, which prevents the inclusion of synaptobrevin in the synaptic vesicle fusion complex and creates a pool of synaptobrevin for exocytosis when synapse activity increases (3). Synaptophysin is also responsible for targeting synaptobrevin 2/VAMP2 to synaptic vesicles, a critical component of the fusion complex (4).

Wiedenmann, B. et al. (1986) Proc Natl Acad Sci USA 83, 3500-4.

Valtorta, F. et al. (2004) Bioessays 26, 445-53.

Arthur, C.P. and Stowell, M.H. (2007) Structure 15, 707-14.

Bonanomi, D. et al. (2007) Biochem J 404, 525-34.

Database Links

UniProt ID:

P08247

Entrez-Gene Id:

6855

View in PhosphoSitePlus®

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